Malaria: influence of Anopheles mosquito saliva on Plasmodium infection
Malaria is caused by Plasmodium protozoa that are transmitted by anopheline mosquitoes.
Plasmodium sporozoites are released with saliva when an infected female mosquito takes a …
Plasmodium sporozoites are released with saliva when an infected female mosquito takes a …
SARS‐CoV‐2‐mediated immune system activation and potential application in immunotherapy
Y Tan, F Tang - Medicinal research reviews, 2021 - Wiley Online Library
Although novel severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)‐mediated
pulmonary inflammation has recently attracted great attention, its pathology and …
pulmonary inflammation has recently attracted great attention, its pathology and …
Current malaria infection, previous malaria exposure, and clinical profiles and outcomes of COVID-19 in a setting of high malaria transmission: an exploratory cohort …
J Achan, A Serwanga, H Wanzira, T Kyagulanyi… - The Lancet …, 2022 - thelancet.com
Background The potential effects of SARS-CoV-2 and Plasmodium falciparum co-infection
on host susceptibility and pathogenesis remain unknown. We aimed to establish the …
on host susceptibility and pathogenesis remain unknown. We aimed to establish the …
Plasmodium falciparum malaria drives epigenetic reprogramming of human monocytes toward a regulatory phenotype
R Guha, A Mathioudaki, S Doumbo, D Doumtabe… - PLoS …, 2021 - journals.plos.org
In malaria-naïve children and adults, Plasmodium falciparum-infected red blood cells (Pf-
iRBCs) trigger fever and other symptoms of systemic inflammation. However, in endemic …
iRBCs) trigger fever and other symptoms of systemic inflammation. However, in endemic …
Increased interleukin-6 levels associated with malaria infection and disease severity: a systematic review and meta-analysis
Abstract Interleukin-6 (IL-6) is generated by immune cells during infection with malaria
parasites and they are associated with the immunopathogenesis of malaria. The present …
parasites and they are associated with the immunopathogenesis of malaria. The present …
Inflammatory cytokines as potential biomarkers for early diagnosis of severe malaria in children in Ghana
E Obeng-Aboagye, A Frimpong, JA Amponsah… - Malaria Journal, 2023 - Springer
Background Severe malaria (SM) is a fatal multi-system disease which accounted for an
estimated 619,000 deaths in 2021. Less than 30% of children presenting with SM are …
estimated 619,000 deaths in 2021. Less than 30% of children presenting with SM are …
Asymptomatic malaria infection is maintained by a balanced pro-and anti-inflammatory response
A Frimpong, J Amponsah, AS Adjokatseh… - Frontiers in …, 2020 - frontiersin.org
Background Pro-and anti-inflammatory cytokines are important mediators of immunity and
are associated with malaria disease outcomes. However, their role in the establishment of …
are associated with malaria disease outcomes. However, their role in the establishment of …
Understanding P. falciparum Asymptomatic Infections: A Proposition for a Transcriptomic Approach
Malaria is still a significant public health burden in the tropics. Infection with malaria causing
parasites results in a wide range of clinical disease presentations, from severe to …
parasites results in a wide range of clinical disease presentations, from severe to …
[HTML][HTML] Age-specific malaria vulnerability and transmission reservoir among children
Purpose The pediatric population, especially under-five children, is highly susceptible to
malaria and accounts for 76% of global malaria deaths according to the World Malaria …
malaria and accounts for 76% of global malaria deaths according to the World Malaria …
Systems analysis shows a role of cytophilic antibodies in shaping innate tolerance to malaria
MJ Lautenbach, V Yman, CS Silva, N Kadri, I Broumou… - Cell Reports, 2022 - cell.com
Natural immunity to malaria develops over time with repeated malaria episodes, but
protection against severe malaria and immune regulation limiting immunopathology, called …
protection against severe malaria and immune regulation limiting immunopathology, called …