Respiratory syncytial virus infection and novel interventions
AC Langedijk, LJ Bont - Nature Reviews Microbiology, 2023 - nature.com
The large global burden of respiratory syncytial virus (RSV) respiratory tract infections in
young children and older adults has gained increased recognition in recent years. Recent …
young children and older adults has gained increased recognition in recent years. Recent …
The road to approved vaccines for respiratory syncytial virus
TJ Ruckwardt - NPJ vaccines, 2023 - nature.com
After decades of work, several interventions to prevent severe respiratory syncytial virus
(RSV) disease in high-risk infant and older adult populations have finally been approved …
(RSV) disease in high-risk infant and older adult populations have finally been approved …
Correlative montage parallel array cryo-tomography for in situ structural cell biology
Imaging large fields of view while preserving high-resolution structural information remains a
challenge in low-dose cryo-electron tomography. Here we present robust tools for montage …
challenge in low-dose cryo-electron tomography. Here we present robust tools for montage …
Coinfection by influenza A virus and respiratory syncytial virus produces hybrid virus particles
Interactions between respiratory viruses during infection affect transmission dynamics and
clinical outcomes. To identify and characterize virus–virus interactions at the cellular level …
clinical outcomes. To identify and characterize virus–virus interactions at the cellular level …
Cryo-electron tomography to study viral infection
M Graham, P Zhang - Biochemical Society Transactions, 2023 - portlandpress.com
Developments in cryo-electron microscopy (cryo-EM) have been interwoven with the study
of viruses ever since its first applications to biological systems. Following the success of …
of viruses ever since its first applications to biological systems. Following the success of …
All Eyes on the Prefusion-Stabilized F Construct, but Are We Missing the Potential of Alternative Targets for Respiratory Syncytial Virus Vaccine Design?
S Schaerlaekens, L Jacobs, K Stobbelaar, P Cos… - Vaccines, 2024 - mdpi.com
Respiratory Syncytial Virus (RSV) poses a significant global health concern as a major
cause of lower respiratory tract infections (LRTIs). Over the last few years, substantial efforts …
cause of lower respiratory tract infections (LRTIs). Over the last few years, substantial efforts …
Structural landscape of the respiratory syncytial virus nucleocapsids
L Gonnin, A Desfosses, M Bacia-Verloop… - Nature …, 2023 - nature.com
Abstract Human Respiratory Syncytial Virus (HRSV) is a prevalent cause of severe
respiratory infections in children and the elderly. The helical HRSV nucleocapsid is a …
respiratory infections in children and the elderly. The helical HRSV nucleocapsid is a …
Imaging analysis reveals budding of filamentous human metapneumovirus virions and direct transfer of inclusion bodies through intercellular extensions
F El Najjar, SR Castillo, CL Moncman, CY Wu, E Isla… - Mbio, 2023 - Am Soc Microbiol
Human metapneumovirus (HMPV) can spread between cells through budding of virus
particles or direct cell-to-cell spread. A network of budding filaments and intercellular …
particles or direct cell-to-cell spread. A network of budding filaments and intercellular …
Assembly of respiratory syncytial virus matrix protein lattice and its coordination with fusion glycoprotein trimers
Respiratory syncytial virus (RSV) is an enveloped, filamentous, negative-strand RNA virus
that causes significant respiratory illness worldwide. RSV vaccines are available, however …
that causes significant respiratory illness worldwide. RSV vaccines are available, however …
[HTML][HTML] Integrating immunoinformatics and computational epitope prediction for a vaccine candidate against respiratory syncytial virus
TL Nguyen, H Kim - Infectious Disease Modelling, 2024 - Elsevier
Respiratory syncytial virus (RSV) poses a significant global health threat, especially affecting
infants and the elderly. Addressing this, the present study proposes an innovative approach …
infants and the elderly. Addressing this, the present study proposes an innovative approach …