Structure, function, and pharmacology of glutamate receptor ion channels
Many physiologic effects of l-glutamate, the major excitatory neurotransmitter in the
mammalian central nervous system, are mediated via signaling by ionotropic glutamate …
mammalian central nervous system, are mediated via signaling by ionotropic glutamate …
Astrocytic processes: from tripartite synapses to the active milieu
A Semyanov, A Verkhratsky - Trends in neurosciences, 2021 - cell.com
We define a new concept of 'active milieu'that unifies all components of nervous tissue
(neuronal and glial compartments, extracellular space, extracellular matrix, and vasculature) …
(neuronal and glial compartments, extracellular space, extracellular matrix, and vasculature) …
Specialized astrocytes mediate glutamatergic gliotransmission in the CNS
Multimodal astrocyte–neuron communications govern brain circuitry assembly and function.
For example, through rapid glutamate release, astrocytes can control excitability, plasticity …
For example, through rapid glutamate release, astrocytes can control excitability, plasticity …
The stressed synapse 2.0: pathophysiological mechanisms in stress-related neuropsychiatric disorders
Stress is a primary risk factor for several neuropsychiatric disorders. Evidence from
preclinical models and clinical studies of depression have revealed an array of structural …
preclinical models and clinical studies of depression have revealed an array of structural …
[HTML][HTML] Behaviorally consequential astrocytic regulation of neural circuits
Astrocytes are a large and diverse population of morphologically complex cells that exist
throughout nervous systems of multiple species. Progress over the last two decades has …
throughout nervous systems of multiple species. Progress over the last two decades has …
Interactions of glial cells with neuronal synapses, from astrocytes to microglia and oligodendrocyte lineage cells
The mammalian brain is a complex organ comprising neurons, glia, and more than 1× 1014
synapses. Neurons are a heterogeneous group of electrically active cells, which form the …
synapses. Neurons are a heterogeneous group of electrically active cells, which form the …
Astrocyte morphology
KT Baldwin, KK Murai, BS Khakh - Trends in Cell Biology, 2023 - cell.com
Astrocytes are predominant glial cells that tile the central nervous system (CNS). A cardinal
feature of astrocytes is their complex and visually enchanting morphology, referred to as …
feature of astrocytes is their complex and visually enchanting morphology, referred to as …
Astrocytic chloride is brain state dependent and modulates inhibitory neurotransmission in mice
Abstract Information transfer within neuronal circuits depends on the balance and recurrent
activity of excitatory and inhibitory neurotransmission. Chloride (Cl−) is the major central …
activity of excitatory and inhibitory neurotransmission. Chloride (Cl−) is the major central …
A biopolymer-gated ionotronic junctionless oxide transistor array for spatiotemporal pain-perception emulation in nociceptor network
Y Li, K Yin, Y Diao, M Fang, J Yang, J Zhang, H Cao… - Nanoscale, 2022 - pubs.rsc.org
Capable of reflecting the location and intensity of external harmful stimuli, a nociceptor
network is of great importance for receiving pain-perception information. However, the …
network is of great importance for receiving pain-perception information. However, the …
The role of astrocyte structural plasticity in regulating neural circuit function and behavior
Brain circuits undergo substantial structural changes during development, driven by the
formation, stabilization, and elimination of synapses. Synaptic connections continue to …
formation, stabilization, and elimination of synapses. Synaptic connections continue to …