Among all nitrogen-containing heterocycles, the 1, 8-naphthyridine scaffold has recently
gained an immense amount of curiosity from numerous researchers across fields of …

Enaminonitrile pyridine derivative was used as a precursor for preparation of fourteen
heterocyclic compounds using both conventional thermal and microwave techniques …

Most bacteria are becoming resistant to almost all of the currently recommended drugs,
leading to difficulty in their treatment. The present study focused on evaluating the …

Tuberculosis (TB) is caused by Mycobacterium tuberculosis (Mtb) and remains a significant
global public health concern, with many new cases reported annually. Despite …

Heterocyclic scaffolds are important from both academic and industrial points of view. Due to
their biological and pharmacological activities, they are useful intermediates in organic …

A carbene-catalyzed reaction to synthesize a chiral quinazolinone with a new activation
mode of an “aniline-like” N–H moiety is disclosed. Addition of the nitrogen atom of diphenyl …

Four 1, 8-naphthyridine derivatives (1a–1d) with different organelle targeting abilities were
obtained using the Knoevenagel condensation reaction of 1, 8-naphthyridine with 4-(N, N …

naphthyridines are synthesized using a four-component, one-pot approach. This method
includes the reaction of aromatic aldehyde, malononitrile, 1, 6-dimethylpyridin-2 (1H)-one …

The present work demonstrates the novel compounds of 5-(2-methyl-1, 8-naphthyridin-3-yl)-
1, 3, 4-oxadiazol-2-amine and its derivatives using symmetrical anhydrides. The synthesized …

Naphthyridine scaffold is a nitrogen-containing heterocyclic compound known for its
versatile biological activities. The structure-activity relationship (SAR) has shown that …