LPS-induced murine neuroinflammation model: main features and suitability for pre-clinical assessment of nutraceuticals

M Nava Catorce, G Gevorkian - Current neuropharmacology, 2016 - ingentaconnect.com
Neuroinflammation is an important feature in the pathogenesis and progression of
neurodegenerative diseases such as Alzheimer´ s disease (AD), Parkinson´ s disease (PD) …

Research progress of glycyrrhizic acid on antiviral activity

ZG Sun, TT Zhao, N Lu, YA Yang… - Mini reviews in …, 2019 - ingentaconnect.com
Glycyrrhizic acid (GA), a triterpene isolated from the roots and rhizomes of licorice, named
Glycyrrhiza glabra, is the principal bioactive ingredient of anti-viral, anti-inflammatory and …

Review of Constituents and Biological Activities of Triterpene Saponins from Glycyrrhizae Radix et Rhizoma and Its Solubilization Characteristics

F Li, B Liu, T Li, Q Wu, Z Xu, Y Gu, W Li, P Wang, T Ma… - Molecules, 2020 - mdpi.com
Glycyrrhizae Radix et Rhizoma is regarded as one of the most popular and commonly used
herbal medicines and has been used in traditional Chinese medicine (TCM) prescriptions …

Melatonin modulates the aggravation of pyroptosis, necroptosis, and neuroinflammation following cerebral ischemia and reperfusion injury in obese rats

N Yawoot, J Sengking, P Govitrapong… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Obesity is well-established as a common comorbidity in ischemic stroke. The increasing
evidence has revealed that it also associates with the exacerbation of brain pathologies …

Targeting high-mobility group box protein 1 (HMGB1) in pediatric traumatic brain injury: Chronic neuroinflammatory, behavioral, and epileptogenic consequences

KM Webster, SR Shultz, E Ozturk, LK Dill, M Sun… - Experimental …, 2019 - Elsevier
High mobility group box protein-1 (HMGB1) has been implicated as a key mediator of
neuroinflammation and neurodegeneration in a range of neurological conditions including …

Potential therapeutic effect of traditional Chinese medicine on coronavirus disease 2019: a review

Q Qiu, Y Huang, X Liu, F Huang, X Li, L Cui… - Frontiers in …, 2020 - frontiersin.org
The Coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory
syndrome coronavirus 2 has been rapidly spreading globally and has caused worldwide …

Analysis of the network pharmacology and the structure-activity relationship of glycyrrhizic acid and glycyrrhetinic acid

Q Ni, Y Gao, X Yang, Q Zhang, B Guo, J Han… - Frontiers in …, 2022 - frontiersin.org
Licorice, a herbal product derived from the root of Glycyrrhiza species, has been used as a
sweetening agent and traditional herbal medicine for hundreds of years. Glycyrrhizic acid …

[HTML][HTML] Magnesium isoglycyrrhizinate ameliorates radiation-induced pulmonary fibrosis by inhibiting fibroblast differentiation via the p38MAPK/Akt/Nox4 pathway

Q Yang, P Zhang, T Liu, X Zhang, X Pan, Y Cen… - Biomedicine & …, 2019 - Elsevier
Radiation-induced pulmonary fibrosis (RIPF) is a severe complication in patients treated
with thoracic irradiation. Until now, there are no effective therapeutic drugs for RIPF. In the …

[HTML][HTML] Role of plant-derived natural compounds in experimental autoimmune encephalomyelitis: a review of the treatment potential and development strategy

YX Guo, Y Zhang, YH Gao, SY Deng… - Frontiers in …, 2021 - frontiersin.org
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system that is
mainly mediated by pathological T-cells. Experimental autoimmune encephalomyelitis …

Glycyrrhizic acid ameliorates mitochondrial function and biogenesis against aluminum toxicity in PC12 cells

M Rashedinia, J Saberzadeh, T Khosravi Bakhtiari… - Neurotoxicity …, 2019 - Springer
Glycyrrhizic acid (GA) is the most effective ingredient in the root of licorice, with important
pharmacological effects. We investigate the effects of GA on mitochondrial function and …