Normothermic machine perfusion of the kidney: better conditioning and repair?
SA Hosgood, E van Heurn… - Transplant …, 2015 - Wiley Online Library
Kidney transplantation is limited by hypothermic preservation techniques. Prolonged periods
of cold ischaemia increase the risk of early graft dysfunction and reduce long‐term survival …
of cold ischaemia increase the risk of early graft dysfunction and reduce long‐term survival …
Extended-criteria donors in liver transplantation Part II: reviewing the impact of extended-criteria donors on the complications and outcomes of liver transplantation
Extended-criteria donors (ECDs) have an impact on early allograft dysfunction (EAD), biliary
complications, relapse of hepatitis C virus (HCV), and survivals. Early allograft dysfunction …
complications, relapse of hepatitis C virus (HCV), and survivals. Early allograft dysfunction …
[HTML][HTML] Liver preservation with machine perfusion and a newly developed cell-free oxygen carrier solution under subnormothermic conditions
P Fontes, R Lopez, A Van Der Plaats… - American journal of …, 2015 - Elsevier
We describe a new preservation modality combining machine perfusion (MP) at
subnormothermic conditions (21° C) with a new hemoglobin-based oxygen carrier (HBOC) …
subnormothermic conditions (21° C) with a new hemoglobin-based oxygen carrier (HBOC) …
[HTML][HTML] Towards the creation of decellularized organ constructs using irreversible electroporation and active mechanical perfusion
Background Despite advances in transplant surgery and general medicine, the number of
patients awaiting transplant organs continues to grow, while the supply of organs does not …
patients awaiting transplant organs continues to grow, while the supply of organs does not …
[HTML][HTML] “Resuscitation” of marginal liver allografts for transplantation with machine perfusion technology
JA Graham, JV Guarrera - Journal of hepatology, 2014 - Elsevier
As the rate of medically suitable donors remains relatively static worldwide, clinicians have
looked to novel methods to meet the ever-growing demand of the liver transplant waiting …
looked to novel methods to meet the ever-growing demand of the liver transplant waiting …
[HTML][HTML] Biomarkers to assess graft quality during conventional and machine preservation in liver transplantation
CJ Verhoeven, WRR Farid, J de Jonge… - Journal of …, 2014 - Elsevier
A global rising organ shortage necessitates the use of extended criteria donors (ECD) for
liver transplantation (LT). However, poor preservation and extensive ischemic injury of ECD …
liver transplantation (LT). However, poor preservation and extensive ischemic injury of ECD …
Subnormothermic machine perfusion at both 20 C and 30 C recovers ischemic rat livers for successful transplantation
H Tolboom, ML Izamis, N Sharma, JM Milwid… - Journal of Surgical …, 2012 - Elsevier
BACKGROUND: Utilizing livers from donors after cardiac death could significantly expand
the donor pool. We have previously shown that normothermic (37° C) extracorporeal liver …
the donor pool. We have previously shown that normothermic (37° C) extracorporeal liver …
[HTML][HTML] Oxygen generating biomaterials preserve skeletal muscle homeostasis under hypoxic and ischemic conditions
Provision of supplemental oxygen to maintain soft tissue viability acutely following trauma in
which vascularization has been compromised would be beneficial for limb and tissue …
which vascularization has been compromised would be beneficial for limb and tissue …
[HTML][HTML] Machine perfusion in liver transplantation as a tool to prevent non-anastomotic biliary strictures: rationale, current evidence and future directions
PD Weeder, R van Rijn, RJ Porte - Journal of hepatology, 2015 - Elsevier
The high incidence of non-anastomotic biliary strictures (NAS) after transplantation of livers
from extended criteria donors is currently a major barrier to widespread use of these organs …
from extended criteria donors is currently a major barrier to widespread use of these organs …
Protective effects of hypothermic ex vivo perfusion on ischemia/reperfusion injury and transplant outcomes
SD Henry, JV Guarrera - Transplantation reviews, 2012 - Elsevier
Hypothermic machine preservation (HMP) has been used in renal transplantation since the
late 1960s with recent robust prospective, multicenter data showing lower rates of delayed …
late 1960s with recent robust prospective, multicenter data showing lower rates of delayed …