Gastrointestinal system

LK Cheng, G O'Grady, P Du, JU Egbuji… - … Systems Biology and …, 2010 - Wiley Online Library
The functions of the gastrointestinal (GI) tract include digestion, absorption, excretion, and
protection. In this review, we focus on the electrical activity of the stomach and small …

Global, regional, and national age-sex-specific mortality and life expectancy, 1950–2017: a systematic analysis for the Global Burden of Disease Study 2017

D Dicker, G Nguyen, D Abate, KH Abate, SM Abay… - The lancet, 2018 - thelancet.com
Background Assessments of age-specific mortality and life expectancy have been done by
the UN Population Division, Department of Economics and Social Affairs (UNPOP), the …

Mechanics of the stomach: A review of an emerging field of biomechanics

S Brandstaeter, SL Fuchs, RC Aydin… - GAMM …, 2019 - Wiley Online Library
Mathematical and computational modeling of the stomach is an emerging field of
biomechanics where several complex phenomena, such as gastric electrophysiology, fluid …

A complete biomechanical model of Hydra contractile behaviors, from neural drive to muscle to movement

H Wang, J Swore, S Sharma… - Proceedings of the …, 2023 - National Acad Sciences
How does neural activity drive muscles to produce behavior? The recent development of
genetic lines in Hydra that allow complete calcium imaging of both neuronal and muscle …

Targeting ion channels for the treatment of gastrointestinal motility disorders

A Beyder, G Farrugia - Therapeutic advances in …, 2012 - journals.sagepub.com
Gastrointestinal (GI) functional and motility disorders are highly prevalent and responsible
for long-term morbidity and sometimes mortality in the affected patients. It is estimated that …

Rapid high‐amplitude circumferential slow wave propagation during normal gastric pacemaking and dysrhythmias

G O'Grady, P Du… - …, 2012 - Wiley Online Library
Background Gastric slow waves propagate aborally as rings of excitation. Circumferential
propagation does not normally occur, except at the pacemaker region. We hypothesized that …

Progress in mathematical modeling of gastrointestinal slow wave abnormalities

P Du, S Calder, TR Angeli, S Sathar… - Frontiers in …, 2018 - frontiersin.org
Gastrointestinal (GI) motility is regulated in part by electrophysiological events called slow
waves, which are generated by the interstitial cells of Cajal (ICC). Slow waves propagate by …

Quantitative cellular description of gastric slow wave activity

A Corrias, ML Buist - American Journal of Physiology …, 2008 - journals.physiology.org
Interstitial cells of Cajal (ICC) are responsible for the spontaneous and omnipresent
electrical activity in the stomach. A quantitative description of the intracellular processes …

Mapping and modeling gastrointestinal bioelectricity: from engineering bench to bedside

LK Cheng, P Du, G O'Grady - Physiology, 2013 - journals.physiology.org
A key discovery in gastrointestinal motility has been the central role played by interstitial
cells of Cajal (ICC) in generating electrical slow waves that coordinate contractions …

Neural regulation of slow waves and phasic contractions in the distal stomach: a mathematical model

ON Athavale, R Avci, AR Clark… - Journal of Neural …, 2024 - iopscience.iop.org
Objective. Neural regulation of gastric motility occurs partly through the regulation of gastric
bioelectrical slow waves (SWs) and phasic contractions. The interaction of the tissues and …