The annotation of small molecules remains a major challenge in untargeted mass
spectrometry-based metabolomics. We here critically discuss structured elucidation …

Reversed-phase high-performance liquid chromatography (RP-HPLC) is the most popular
chromatographic mode, accounting for more than 90% of all separations. HPLC itself owes …

Hydrophilic interaction liquid chromatography (HILIC) provides an alternative approach to
effectively separate small polar compounds on polar stationary phases. The purpose of this …

In recent years, several studies have reported the beneficial effects of antioxidant peptides in
delaying oxidation reactions. Thus, a growing number of food proteins have been …

An overview of the state-of-the-art in LC enantiomer separation is presented. This tutorial
review is mainly focused on mechanisms of chiral recognition and enantiomer distinction of …

The structural elucidation of small molecules using mass spectrometry plays an important
role in modern life sciences and bioanalytical approaches. This review covers different soft …

Metabolomics is an emerging field of postgenomic biology concerned with comprehensive
analysis of small molecules in biological systems. However, difficulties associated with the …

Covering: up to 2013. Plant metabolomics is a relatively recent research field that has
gained increasing interest in the past few years. Up to the present day numerous review …

Recent applications of retention modelling in liquid chromatography (2015–2020) are
comprehensively reviewed. The fundamentals of the field, which date back much longer, are …

The demand for rapid column screening, computer-assisted method development and
method transfer, and unambiguous compound identification by LC/MS analyses has pushed …