The current status of mesenchymal stromal cells: controversies, unresolved issues and some promising solutions to improve their therapeutic efficacy
D García-Bernal, M García-Arranz… - Frontiers in Cell and …, 2021 - frontiersin.org
Mesenchymal stromal cells (MSCs) currently constitute the most frequently used cell type in
advanced therapies with different purposes, most of which are related with inflammatory …
advanced therapies with different purposes, most of which are related with inflammatory …
Nucleic acid delivery to mesenchymal stem cells: a review of nonviral methods and applications
A Hamann, A Nguyen, AK Pannier - Journal of biological engineering, 2019 - Springer
Abstract Background Mesenchymal stem cells (MSCs) are multipotent stem cells that can be
isolated and expanded from many tissues, and are being investigated for use in cell …
isolated and expanded from many tissues, and are being investigated for use in cell …
Comparison of the biological characteristics of mesenchymal stem cells derived from the human placenta and umbilical cord
M Wu, R Zhang, Q Zou, Y Chen, M Zhou, X Li, R Ran… - Scientific Reports, 2018 - nature.com
Mesenchymal stem/stromal cells (MSCs) derived from placental tissue show great
therapeutic potential and have been used in medical treatment, but the similarity and …
therapeutic potential and have been used in medical treatment, but the similarity and …
[HTML][HTML] Therapeutic angiogenesis-based strategy for peripheral artery disease
J Han, L Luo, O Marcelina, V Kasim, S Wu - Theranostics, 2022 - ncbi.nlm.nih.gov
Peripheral artery disease (PAD) poses a great challenge to society, with a growing
prevalence in the upcoming years. Patients in the severe stages of PAD are prone to …
prevalence in the upcoming years. Patients in the severe stages of PAD are prone to …
A deep proteome analysis identifies the complete secretome as the functional unit of human cardiac progenitor cells
Rationale: Cardiac progenitor cells are an attractive cell type for tissue regeneration, but
their mechanism for myocardial remodeling is still unclear. Objective: This investigation …
their mechanism for myocardial remodeling is still unclear. Objective: This investigation …
Injectable supramolecular ureidopyrimidinone hydrogels provide sustained release of extracellular vesicle therapeutics
EA Mol, Z Lei, MT Roefs, MH Bakker… - Advanced …, 2019 - Wiley Online Library
Extracellular vesicles (EVs) are small vesicles secreted by cells and have gained increasing
interest as both drug delivery vehicles or as cell‐free therapeutics for regenerative medicine …
interest as both drug delivery vehicles or as cell‐free therapeutics for regenerative medicine …
[HTML][HTML] Intramuscular administration potentiates extended dwell time of mesenchymal stromal cells compared to other routes
LR Braid, CA Wood, DM Wiese, BN Ford - Cytotherapy, 2018 - Elsevier
Abstract Background Mesenchymal stromal cells (MSCs) offer great potential for diverse
clinical applications. However, conventional systemic infusion of MSCs limits their …
clinical applications. However, conventional systemic infusion of MSCs limits their …
Heterogeneity of in vitro expanded mesenchymal stromal cells and strategies to improve their therapeutic actions
L Olmedo-Moreno, Y Aguilera, C Baliña-Sánchez… - Pharmaceutics, 2022 - mdpi.com
Beneficial properties of mesenchymal stromal cells (MSCs) have prompted their use in
preclinical and clinical research. Accumulating evidence has been provided for the …
preclinical and clinical research. Accumulating evidence has been provided for the …
State of the field: cellular and exosomal therapeutic approaches in vascular regeneration
EP Tracy, V Stielberg, G Rowe… - American Journal …, 2022 - journals.physiology.org
Pathologies of the vasculature including the microvasculature are often complex in nature,
leading to loss of physiological homeostatic regulation of patency and adequate perfusion to …
leading to loss of physiological homeostatic regulation of patency and adequate perfusion to …
Mesenchymal stem cell transplantation for ischemic diseases: mechanisms and challenges
TT Van Nguyen, NB Vu, P Van Pham - Tissue Engineering and …, 2021 - Springer
Ischemic diseases are conditions associated with the restriction or blockage of blood supply
to specific tissues. These conditions can cause moderate to severe complications in …
to specific tissues. These conditions can cause moderate to severe complications in …