[HTML][HTML] Amelogenesis imperfecta; genes, proteins, and pathways
Amelogenesis imperfecta (AI) is the name given to a heterogeneous group of conditions
characterized by inherited developmental enamel defects. AI enamel is abnormally thin, soft …
characterized by inherited developmental enamel defects. AI enamel is abnormally thin, soft …
Molecular and cellular mechanisms of tooth development, homeostasis and repair
T Yu, OD Klein - Development, 2020 - journals.biologists.com
The tooth provides an excellent system for deciphering the molecular mechanisms of
organogenesis, and has thus been of longstanding interest to developmental and stem cell …
organogenesis, and has thus been of longstanding interest to developmental and stem cell …
[HTML][HTML] Amelogenesis imperfecta: Next-generation sequencing sheds light on Witkop's classification
A Bloch-Zupan, T Rey, A Jimenez-Armijo… - Frontiers in …, 2023 - frontiersin.org
Amelogenesis imperfecta (AI) is a heterogeneous group of genetic rare diseases disrupting
enamel development (Smith et al., Front Physiol, 2017a, 8, 333). The clinical enamel …
enamel development (Smith et al., Front Physiol, 2017a, 8, 333). The clinical enamel …
A targeted next-generation sequencing assay for the molecular diagnosis of genetic disorders with orodental involvement
Background Orodental diseases include several clinically and genetically heterogeneous
disorders that can present in isolation or as part of a genetic syndrome. Due to the vast …
disorders that can present in isolation or as part of a genetic syndrome. Due to the vast …
Mutations in RELT cause autosomal recessive amelogenesis imperfecta
Amelogenesis imperfecta (AI) is a collection of isolated (non‐syndromic) inherited diseases
affecting dental enamel formation or a clinical phenotype in syndromic conditions. We …
affecting dental enamel formation or a clinical phenotype in syndromic conditions. We …
[HTML][HTML] Biomimetic mineralisation systems for in situ enamel restoration inspired by amelogenesis
J Wang, Z Liu, B Ren, Q Wang, J Wu, N Yang… - Journal of Materials …, 2021 - Springer
Caries and dental erosion are common oral diseases. Traditional treatments involve the
mechanical removal of decay and filling but these methods are not suitable for cases …
mechanical removal of decay and filling but these methods are not suitable for cases …
[HTML][HTML] Mutations in the pH-sensing G-protein-coupled receptor GPR68 cause amelogenesis imperfecta
Amelogenesis is the process of dental enamel formation, leading to the deposition of the
hardest tissue in the human body. This process requires the intricate regulation of ion …
hardest tissue in the human body. This process requires the intricate regulation of ion …
Coemergence of the amphipathic helix on ameloblastin with mammalian prismatic enamel
To investigate correlation between the ameloblastin (Ambn) amino acid sequence and the
emergence of prismatic enamel, a notable event in the evolution of ectodermal hard tissues …
emergence of prismatic enamel, a notable event in the evolution of ectodermal hard tissues …
[HTML][HTML] Overexpression of ameloblastin in secretory ameloblasts results in demarcated, hypomineralized opacities in enamel
YHP Chun, C Tan, O Villanueva, ME Colley… - Frontiers in …, 2024 - frontiersin.org
Introduction: Developmental defects of the enamel manifest before tooth eruption and
include amelogenesis imperfecta, a rare disease of underlying gene mutations, and molar …
include amelogenesis imperfecta, a rare disease of underlying gene mutations, and molar …
Molecular‐based phenotype variations in amelogenesis imperfecta
J Dong, W Ruan, X Duan - Oral Diseases, 2023 - Wiley Online Library
Amelogenesis imperfecta (AI) is one of the typical dental genetic diseases in human. It can
occur isolatedly or as part of a syndrome. Previous reports have mainly clarified the types …
occur isolatedly or as part of a syndrome. Previous reports have mainly clarified the types …