Alterations of endothelial cells and the vasculature play a central role in the pathogenesis of
a broad spectrum of the most dreadful of human diseases, as endothelial cells have the key …

For most patients with chronic myeloid leukemia, tyrosine kinase inhibitors (TKIs) have
turned a fatal disease into a manageable chronic condition. Imatinib, the first BCR-ABL1 TKI …

Background—Data are limited on the presence, distribution, and extent of subclinical
atherosclerosis in middle-aged populations. Methods and Results—The PESA (Progression …

Burnout is characterized by emotional exhaustion, physical fatigue, and cognitive weariness,
resulting from prolonged exposure to work-related stress. The authors review the …

Hyperlipidemia - Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe
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With an increasing global burden of coronary artery disease (CAD), early detection and
timely management of risk factors are crucial to reduce morbidity and mortality in such …

Platelets are essential for clotting in the blood and maintenance of normal hemostasis.
Under pathologic conditions such as atherosclerosis, vascular injury often results in …

Chronic obstructive pulmonary disease (COPD) and atherosclerosis are chronic irreversible
diseases, that share a number of common causative factors including cigarette smoking …

Atherothrombosis is a complex disease in which cholesterol deposition, inflammation, and
thrombus formation play a major role. Rupture of high-risk, vulnerable plaques is …

The vascular endothelium occupies a catalog of functions that contribute to the homeostasis
of the cardiovascular system. It is a physically active barrier between circulating blood and …