Functional brain networks in the evaluation of patients with neurodegenerative disorders

M Perovnik, T Rus, KA Schindlbeck… - Nature Reviews …, 2023 - nature.com
Network analytical tools are increasingly being applied to brain imaging maps of resting
metabolic activity (PET) or blood oxygenation-dependent signals (functional MRI) to …

Network imaging biomarkers: insights and clinical applications in Parkinson's disease

KA Schindlbeck, D Eidelberg - The Lancet Neurology, 2018 - thelancet.com
Parkinson's disease presents several practical challenges: it can be difficult to distinguish
from atypical parkinsonian syndromes, clinical ratings can be insensitive as markers of …

The default mode network and cognition in Parkinson's disease: A multimodal resting‐state network approach

MC Ruppert, A Greuel, J Freigang… - Human brain …, 2021 - Wiley Online Library
Involvement of the default mode network (DMN) in cognitive symptoms of Parkinson's
disease (PD) has been reported by resting‐state functional MRI (rsfMRI) studies. However …

Emergent functional network effects in Parkinson disease

C Gratton, JM Koller, W Shannon, DJ Greene… - Cerebral …, 2019 - academic.oup.com
The hallmark pathology underlying Parkinson disease (PD) is progressive synucleinopathy,
beginning in caudal brainstem that later spreads rostrally. However, the primarily subcortical …

Brain molecular connectivity in neurodegenerative diseases: recent advances and new perspectives using positron emission tomography

A Sala, D Perani - Frontiers in neuroscience, 2019 - frontiersin.org
Positron emission tomography (PET) represents a unique molecular tool to get in vivo
access to a wide spectrum of biological and neuropathological processes, of crucial …

Parkinson disease-related brain metabolic patterns and neurodegeneration in isolated REM sleep behavior disorder

JH Shin, JY Lee, YK Kim, EJ Yoon, H Kim, H Nam… - Neurology, 2021 - AAN Enterprises
Objective To elucidate the role of Parkinson disease (PD)-related brain metabolic patterns
as a biomarker in isolated REM sleep behavior disorder (iRBD) for future disease …

[HTML][HTML] Gender differences in dopaminergic system dysfunction in de novo Parkinson's disease clinical subtypes

C Boccalini, G Carli, A Pilotto, A Padovani… - Neurobiology of …, 2022 - Elsevier
Parkinson's disease (PD) is characterized by heterogeneity in clinical syndromes, prognosis,
and pathophysiology mechanisms. Gender differences in neural anatomy and function are …

Scaled subprofile modeling and convolutional neural networks for the identification of Parkinson's disease in 3D nuclear imaging data

OM Manzanera, SK Meles, KL Leenders… - … journal of neural …, 2019 - World Scientific
Over the last years convolutional neural networks (CNNs) have shown remarkable results in
different image classification tasks, including medical imaging. One area that has been less …

Covariance statistics and network analysis of brain PET imaging studies

M Veronese, L Moro, M Arcolin, O Dipasquale… - Scientific Reports, 2019 - nature.com
The analysis of structural and functional neuroimaging data using graph theory has
increasingly become a popular approach for visualising and understanding anatomical and …

The role of graph theory in evaluating brain network alterations in frontotemporal dementia

S Nigro, M Filardi, B Tafuri, R De Blasi… - Frontiers in …, 2022 - frontiersin.org
Frontotemporal dementia (FTD) is a spectrum of clinical syndromes that affects personality,
behavior, language, and cognition. The current diagnostic criteria recognize three main …