[HTML][HTML] Lipid sensing by PPARα: Role in controlling hepatocyte gene regulatory networks and the metabolic response to fasting

A Fougerat, J Bruse, A Polizzi, A Montagner… - Progress in Lipid …, 2024 - Elsevier
Peroxisome proliferator-activated receptors (PPARs) constitute a small family of three
nuclear receptors that act as lipid sensors, and thereby regulate the transcription of genes …

Exogenous ketone esters as a potential therapeutic for treatment of sarcopenic obesity

SE Deemer, BM Roberts, DL Smith… - … of Physiology-Cell …, 2024 - journals.physiology.org
Identifying effective treatment (s) for sarcopenia and sarcopenic obesity is of paramount
importance as the global population advances in age and obesity continues to be a …

Acute effects of a ketone monoester, whey protein, or their co-ingestion on mTOR trafficking and protein-protein co-localization in human skeletal muscle

SJ Hannaian, J Lov, Z Cheng-Boivin… - … of Physiology-Cell …, 2024 - journals.physiology.org
We recently demonstrated that acute oral ketone monoester intake induces a stimulation of
postprandial myofibrillar protein synthesis rates comparable to that elicited following the …

Wearable microfluidic electrochemical sensor integrated with iontophoresis for non-invasive sweat ketone monitoring

Y Shen, G Chen, Y Chen, Y Gao, C Hou, K Liao… - Sensors and Actuators B …, 2024 - Elsevier
The detection of β-hydroxybutyrate (β-HB) is crucial for the rapid diagnosis of diabetic
ketoacidosis and health management. However, daily monitoring of dynamically changing β …

Association patterns of ketone bodies with the risk of adverse outcomes according to diabetes status

J Li, Y Sun, B Yu, L Cai, W Shen… - Diabetes, Obesity …, 2024 - Wiley Online Library
Aim To investigate the associations between ketone bodies (KB) and multiple adverse
outcomes including cardiovascular disease (CVD), chronic kidney disease (CKD) and all …

[HTML][HTML] Effects of a Carbohydrate Meal on Lipolysis

K Kempf, S Martin - Nutrients, 2024 - mdpi.com
Background: Due to the increasing prevalence of obesity and type 2 diabetes, effective
dietary recommendations are needed. Previously, we developed the low-insulin method: by …

Glutathione and a Pool of Metabolites Partly Related to Oxidative Stress Are Associated with Low and High Myopia in an Altered Bioenergetic Environment

S Mérida, A Návea, C Desco, B Celda… - Antioxidants, 2024 - mdpi.com
Oxidative stress forms part of the molecular basis contributing to the development and
manifestation of myopia, a refractive error with associated pathology that is increasingly …

[HTML][HTML] Genetics, pharmacotherapy, and dietary interventions in childhood obesity

JE Son - Journal of Pharmacy & Pharmaceutical Sciences, 2024 - frontierspartnerships.org
Childhood obesity has emerged as a major global health issue, contributing to the increased
prevalence of chronic conditions and adversely affecting the quality of life and future …

[HTML][HTML] Resistant Potato Starch Supplementation Reduces Serum Free Fatty Acid Levels and Influences Bile Acid Metabolism

JR Bush, I Iwuamadi, J Han, DJ Schibli, DR Goodlett… - Metabolites, 2024 - mdpi.com
Background: Resistant starches, such as high-amylose maize starch and resistant potato
starch (RPS), have prebiotic effects that are linked to improved metabolism at> 15 g/day, but …

Metabolic Contrasts: Fatty Acid Oxidation and Ketone Bodies in Healthy Brains vs. Glioblastoma Multiforme

C Tamas, F Tamas, A Kovecsi, A Cehan… - International Journal of …, 2024 - mdpi.com
The metabolism of glucose and lipids plays a crucial role in the normal homeostasis of the
body. Although glucose is the main energy substrate, in its absence, lipid metabolism …