Gout is a picturesque presentation of uric acid disturbance. It is the most well understood
and described type of arthritis. Its epidemiology is studied. New insights into the …

Urate is a cause of gout, kidney stones, and acute kidney injury from tumor lysis syndrome,
but its relationship to kidney disease, cardiovascular disease, and diabetes remains …

Gout is a crystal-deposition disease that results from chronic elevation of uric acid levels
above the saturation point for monosodium urate (MSU) crystal formation. Initial presentation …

Elevated serum urate levels cause gout and correlate with cardiometabolic diseases via
poorly understood mechanisms. We performed a trans-ancestry genome-wide association …

A central aspect of the pathogenesis of gout is elevated urate concentrations, which lead to
the formation of monosodium urate crystals. The clinical features of gout result from an …

Gout is a common inflammatory arthritis caused by the deposition of sodium urate crystals in
the joints. Hyperuricemia is the fundamental factor of gout. The onset of hyperuricemia is …

Gout is an inflammatory condition caused by elevated serum urate (SU), a condition known
as hyperuricemia (HU). Genetic variations, including single nucleotide polymorphisms …

Genome-wide association studies that scan the genome for common genetic variants
associated with phenotype have greatly advanced medical knowledge. Hyperuricemia is no …

Elevated serum urate concentration is the primary cause of gout. Understanding the
processes that affect serum urate concentration is important for understanding the etiology of …

Gout arthritis (GA) is a common and curable type of inflammatory arthritis that has been
attributed to a combination of genetic, environmental and metabolic factors. Chronic …