[HTML][HTML] Early social adversity, altered brain functional connectivity, and mental health

NE Holz, O Berhe, S Sacu, E Schwarz, J Tesarz… - Biological …, 2023 - Elsevier
Early adverse environmental exposures during brain development are widespread risk
factors for the onset of severe mental disorders and strong and consistent predictors of …

Why and how does early adversity influence development? Toward an integrated model of dimensions of environmental experience

BJ Ellis, MA Sheridan, J Belsky… - Development and …, 2022 - cambridge.org
Two extant frameworks–the harshness-unpredictability model and the threat-deprivation
model–attempt to explain which dimensions of adversity have distinct influences on …

Learning about safety: Conditioned inhibition as a novel approach to fear reduction targeting the developing brain

P Odriozola, DG Gee - American journal of psychiatry, 2021 - Am Psychiatric Assoc
Adolescence is a peak time for the onset of psychiatric disorders, with anxiety disorders
being the most common and affecting as many as 30% of youths. A core feature of anxiety …

[HTML][HTML] Childhood trauma and brain structure in children and adolescents

M Peverill, ML Rosen, LA Lurie, KA Sambrook… - Developmental …, 2023 - Elsevier
The dimensional model of adversity proposes that experiences of threat and deprivation
have distinct neurodevelopmental consequences. We examined these dimensions …

The impact of psychosocial adversity on brain and behaviour: an overview of existing knowledge and directions for future research

N Vaidya, AF Marquand, F Nees, S Siehl… - Molecular …, 2024 - nature.com
Environmental experiences play a critical role in shaping the structure and function of the
brain. Its plasticity in response to different external stimuli has been the focus of research …

A coordinate-based meta-analysis of human amygdala connectivity alterations related to early life adversities

EJ Kraaijenvanger, T Banaschewski, SB Eickhoff… - Scientific reports, 2023 - nature.com
By affecting core neurobiological systems early in development, early life adversities (ELAs)
might confer latent vulnerability to future psychopathologies. This coordinate-based meta …

Neural circuitry involved in conditioned inhibition via safety signal learning is sensitive to trauma exposure

S Kribakaran, P Odriozola, EM Cohodes… - Neurobiology of …, 2022 - Elsevier
Exposure to trauma throughout the lifespan is prevalent and increases the likelihood for the
development of mental health conditions such as anxiety and post-traumatic stress disorder …

Neuroimmune mechanisms connecting violence with internalizing symptoms: A high‐dimensional multimodal mediation analysis

ER Butler, N Samia, S White, C Gratton… - Human brain …, 2024 - Wiley Online Library
Violence exposure is associated with worsening anxiety and depression symptoms among
adolescents. Mechanistically, social defeat stress models in mice indicate that violence …

Strengthening through adversity: The hormesis model in developmental psychopathology

A Oshri, CJ Howard, L Zhang, A Reck, Z Cui… - Development and …, 2024 - cambridge.org
Background: Employing a developmental psychopathology framework, we tested the utility
of the hormesis model in examining the strengthening of children and youth through limited …

Future Directions in the Mental Health of Transgender Youth: Towards a Social-Affective Developmental Model of Health Disparity

S Sequeira, T Carmel, B Tervo-Clemmens… - Journal of Clinical …, 2023 - Taylor & Francis
Mental health disparities in transgender and gender diverse (TGD) youth are well-
documented. These disparities are often studied in the context of minority stress theory, and …