Brain lipidomics: From functional landscape to clinical significance

JH Yoon, Y Seo, YS Jo, S Lee, E Cho… - Science …, 2022 - science.org
Lipids are crucial components of cellular function owing to their role in membrane formation,
intercellular signaling, energy storage, and homeostasis maintenance. In the brain, lipid …

The role of lipids in exosome biology and intercellular communication: Function, analytics and applications

J Donoso‐Quezada, S Ayala‐Mar, J González‐Valdez - Traffic, 2021 - Wiley Online Library
Exosomes are extracellular vesicles that in recent years have received special attention for
their regulatory functions in numerous biological processes. Recent evidence suggests a …

Lipidomics from sample preparation to data analysis: a primer

T Züllig, M Trötzmüller, HC Köfeler - Analytical and bioanalytical chemistry, 2020 - Springer
Lipids are amongst the most important organic compounds in living organisms, where they
serve as building blocks for cellular membranes as well as energy storage and signaling …

Ozone-enabled fatty acid discovery reveals unexpected diversity in the human lipidome

JP Menzel, RSE Young, AH Benfield, JS Scott… - Nature …, 2023 - nature.com
Fatty acid isomers are responsible for an under-reported lipidome diversity across all
kingdoms of life. Isomers of unsaturated fatty acids are often masked in contemporary …

Ultraviolet photodissociation mass spectrometry for analysis of biological molecules

JS Brodbelt, LJ Morrison, I Santos - Chemical reviews, 2019 - ACS Publications
The development of new ion-activation/dissociation methods continues to be one of the most
active areas of mass spectrometry owing to the broad applications of tandem mass …

Recurrent topics in mass spectrometry-based metabolomics and lipidomics—standardization, coverage, and throughput

E Rampler, YE Abiead, H Schoeny, M Rusz… - Analytical …, 2020 - ACS Publications
We have come a long way in the last years of developing analytical strategies in
metabolomics. We have seen huge progress in tackling multiplatform measurement, data …

Foodomics: A new approach in food quality and safety

P Balkir, K Kemahlioglu, U Yucel - Trends in Food Science & Technology, 2021 - Elsevier
Background. The progress in the analytical methods in food science and technology brought
about a novel and modern approach concerning human health and food quality and safety …

High resolution mass spectrometry in lipidomics

T Züllig, HC Köfeler - Mass spectrometry reviews, 2021 - Wiley Online Library
The boost of research output in lipidomics during the last decade is tightly linked to improved
instrumentation in mass spectrometry. Associated with this trend is the shift from low …

The role of lipids in Parkinson's disease

H Xicoy, B Wieringa, GJM Martens - Cells, 2019 - mdpi.com
Parkinson's disease (PD) is a neurodegenerative disease characterized by a progressive
loss of dopaminergic neurons from the nigrostriatal pathway, formation of Lewy bodies, and …

Quantitative subcellular reconstruction reveals a lipid mediated inter-organelle biogenesis network

RG Lee, DL Rudler, SA Raven, L Peng, A Chopin… - Nature Cell …, 2024 - nature.com
The structures and functions of organelles in cells depend on each other but have not been
systematically explored. We established stable knockout cell lines of peroxisomal, Golgi and …