Virtual reality (VR) environments are increasingly being used by neuroscientists to simulate
natural events and social interactions. VR creates interactive, multimodal sensory stimuli that …

The mammalian hippocampal formation contains several distinct populations of neurons
involved in representing self-position and orientation. These neurons, which include place …

Knowing where we are, where we have been, and where we are going is critical to many
behaviors, including navigation and memory. One potential neuronal mechanism underlying …

Grid cells in the entorhinal cortex appear to represent spatial location via a triangular
coordinate system. Such cells, which have been identified in rats, bats and monkeys, are …

The earliest stages of Alzheimer's disease (AD) are characterized by the formation of mature
tangles in the entorhinal cortex and disorientation and confusion when navigating familiar …

The hippocampus and its associated cortical regions in the medial temporal lobe play
essential roles when animals form a cognitive map and use it to achieve their goals. As the …

In many species, spatial navigation is supported by a network of place cells that exhibit
increased firing whenever an animal is in a certain region of an environment. Does this …

Over the past four decades, research has revealed that cells in the hippocampal formation
provide an exquisitely detailed representation of an animal's current location and heading …

Animals can navigate vast distances and often display behaviours or activities that indicate a
detailed, internal spatial representation of their surrounding environment or a 'cognitive …

The entorhinal cortex is one of the first regions to exhibit neurodegeneration in Alzheimer's
disease, and as such identification of entorhinal cortex dysfunction may aid detection of the …