Atherosclerosis is a chronic cardiovascular disease which increases risk of major
cardiovascular events including myocardial infarction and stroke. Elevated plasma …

Objectives Both dimethylarginines are widely bound to chronic kidney disease (CKD). This
study was focused to validate published LC-MS/MS method and compared the measured …

Cadmium (Cd) is a toxic metal inducing a range of adverse effects on organs including liver
and kidneys. However, the underlying molecular mechanisms of Cd-induced intestinal …

Background Alanine: glyoxylate aminotransferase 2 (AGXT2; EC 2.6. 1.44) is the only
enzyme that degrades the R-form of 3-aminoisobutyrate, an intermediate metabolite of …

Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthesis and a
cardiovascular risk factor. Its regulation has been studied extensively in experimental …

Bariatric surgery improves obesity-related comorbidities. Methylarginines are biomarkers of
cardiometabolic risk, liver steatosis, and insulin resistance. Here, we aimed to investigate …

Rheumatoid Arthritis (RA) confers an increased cardiovascular disease (CVD) risk which
accounts for much of the premature morbidity and mortality observed in this population …

No study has shown the relationship between alanine-glyoxylate aminotransferase 2
(AGXT2) single nucleotide polymorphisms (SNPs) and depressive symptoms. The present …

Delayed cerebral ischemia (DCI) often causes poor long-term neurological outcome after
subarachnoidal hemorrhage (SAH). Asymmetric dimethylarginine (ADMA) inhibits nitric …

Objectives The relationship between alanine-glyoxylate aminotransferase 2 (AGXT2) single-
nucleotide polymorphisms (SNPs) and diabetes mellitus (DM) has not been investigated …