Pharmaceutical considerations and metabolic fate of parenteral lipid nanoparticle dosage forms
DF Driscoll, BR Bistrian - Journal of Pharmaceutical Sciences, 2024 - Elsevier
The physical stability of parenteral dispersions for delivery of drugs to patients is of particular
clinical importance, given their general overall superior bioavailability compared to other …
clinical importance, given their general overall superior bioavailability compared to other …
Strategies for Improved pDNA Loading and Protection Using Cationic and Neutral LNPs with Industrial Scalability Potential Using Microfluidic Technology
I Ottonelli, E Adani, A Bighinati, S Cuoghi… - International Journal …, 2024 - Taylor & Francis
Purpose In recent years, microfluidic technologies have become mainstream in producing
gene therapy nanomedicines (NMeds) following the Covid-19 vaccine; however, extensive …
gene therapy nanomedicines (NMeds) following the Covid-19 vaccine; however, extensive …
Cryoprotectant optimization for enhanced stability and transfection efficiency of pDNA-loaded ionizable lipid nanoparticles
HAS Ferreira, SRAS Júnior, KKS de Faria… - International Journal of …, 2024 - Elsevier
Advances in gene therapy, exemplified by mRNA vaccines against COVID-19, highlight the
importance of lipid nanoparticles (LNPs) for nucleic acid delivery despite challenging …
importance of lipid nanoparticles (LNPs) for nucleic acid delivery despite challenging …
Anion exchange-HPLC method for evaluating the encapsulation efficiency of mRNA-loaded lipid nanoparticles using analytical quality by design
S Hara, S Arase, S Sano, T Suzuki, I Mizogaki… - … of Chromatography B, 2024 - Elsevier
Lipid nanoparticles (LNPs) are emerging nucleic acid delivery systems in the development
of mRNA therapeutics such as the severe acute respiratory syndrome coronavirus 2 …
of mRNA therapeutics such as the severe acute respiratory syndrome coronavirus 2 …
Lipid Nanoparticle (LNP) Delivery Vector-Assisted Targeted Controlled Release mRNA Vaccines in Tumor Immunity
L Wu, X Li, X Qian, S Wang, J Liu, J Yan - 2023 - preprints.org
Lipid nanoparticles (LNPs) have attracted extensive attention in tumor immunotherapy in
recent years. The strategy of targeting immune cells in cancer therapy has become a …
recent years. The strategy of targeting immune cells in cancer therapy has become a …
[PDF][PDF] Role of Vaccines in Controlling COVID-19 Pandemic
This chapter thoroughly examines the critical role vaccines have played in the global effort to
combat the unprecedented challenges posed by the SARS-CoV-2 virus. The chapter …
combat the unprecedented challenges posed by the SARS-CoV-2 virus. The chapter …