Male factor accounts for about 30–50% of infertility. A common cause of male infertility is
drug abuse; either illicit or prolonged use of prescribed drugs. This study provides a review …

The future fertility of cancer patients after treatment is a serious concern amongst young
cancer patients. Such chemotherapeutic agents as Methotrexate (MTX), a folic acid …

The genotoxic actions of anti-neoplastic drugs can lead to the development of secondary
cancers in patients in extended remission. One of the most attractive approaches to disease …

The aim of the study was to investigate the protective effect of pyrrolidine dithiocarbamate
(PDTC) against methotrexate (MTX)-induced testicular damage in rats. Forty Wistar albino …

Background/aim: Methotrexate (MTX), used commonly as an antimetabolite drug in cancer
therapy, leads to acute toxic side effects in tissues or organs containing rapidly dividing …

Prolonged use of immunosuppressant medications is occasionally seen in infertile men with
chronic inflammatory conditions; autoimmune disorders; or an organ or hematopoietic stem …

Methotrexate (MTX) is a widely used chemotherapeutic agent but its clinical use is
challenged with different forms of toxicities including testicular injury. The aim of the current …

This study aimed to examine the effects of guarana (Paullinia cupana) on intestinal damage
induced by MTX in mice. Mice were classified into four groups: control, MTX, guarana …

Objective. The current study was aimed to examine the possible ameliorative impacts of MO
leaf extract (MOLE) against MTX‐induced alterations on oxidative stress of mouse spleen …

Objective The present study aimed to investigate the possibility that curcumin (CMN)
protects against methotrexate (MTX)-induced testicular damage by affecting the phospho …