Disintegration is the de-aggregation of particles within tablets upon exposure to aqueous
fluids. Being an essential step in the bioavailability cascade, disintegration is a fundamental …

Abstract Following the first Manufacturing Classification System (MCS) paper, the team
conducted surveys to establish which active pharmaceutical ingredient (API) properties were …

Aqueous-based film coating has become routine in the pharmaceutical industry. This
process eliminates the use of organic solvents and thus avoids economic, environmental …

Understanding interparticle interactions in powder systems is crucial to pharmaceutical
powder processing. Nevertheless, there remains a great challenge in identifying the key …

Continuous twin screw wet granulation is one of the key continuous manufacturing
technologies that have gained significant interest in the pharmaceutical industry as well as …

Appropriate lubrication is important in tablet manufacturing as it lowers punch sticking
propensity and protects tooling by reducing friction between die wall and tablet during tablet …

This book provides an overview of excipients, their functionalities in pharmaceutical dosage
forms, regulation, and selection for pharmaceutical products formulation. It includes …

Manufacturing of active pharmaceutical ingredients (API) is known to produce significantly
larger environmental impacts than manufacturing of commodity chemicals. This prompted …

In formulation development, certain excipients, even though used in small quantities, can
have a significant impact on the processability and performance of the dosage form. In this …

Despite the recent commercialization of several drug products manufactured through
continuous manufacturing techniques, knowledge on the formulation aspect of these …