Oxazole compounds containing nitrogen and oxygen atoms in the five-membered aromatic
ring are readily able to bind with a variety of enzymes and receptors in biological systems …

Isoxazole, constituting an important family of five-membered heterocycles with one oxygen
atom and one nitrogen atom at adjacent positions is of immense importance because of its …

Human longevity has increased dramatically during the past century. More than 20% of the 9
billion population of the world will exceed the age of 60 in 2050. Since the last three …

In the field of drug discovery, isoxazole is a five-membered heterocyclic moiety commonly
found in many commercially available drugs. In view of their enormous significance, it is …

Efficacious protocols have been established to synthesize a structurally privileged Π-
extended coumarin-fused pyridone nucleus by activating the vinylic C (sp2)–H bond of …

Abstract A variety of N-((1, 3-diphenyl-5-aryl-1H-pyrazol-4-yl) sulfonyl) thiophene-2-
carboxamides (7) and N-((5-aryl-3-phenylisoxazol-4-yl) sulfonyl) thiophene-2-carboxamides …

A ruthenium-catalyzed oxidative coupling of vinylene carbonate with isoxazoles has been
developed to achieve the direct C–H formylmethylation of a diverse array of arylisoxazoles …

In this review article, we describe the application, reactivity and synthesis of isoxazole
derivatives, more specifically, the application, reactivity, and synthesis of 3, 5-disubstituted …

Abstract The 1, 3‐dipolar cycloaddition reactions (DCs) of nitrile oxides (NOs) to alkenes
and alkynes are useful methods for the synthesis of 2‐isoxazolines and isoxazoles …

High levels of catalyst control are demonstrated in determining the positional selectivity in C–
H alkenylation of isoxazoles. A cationic rhodium-mediated, strong-directing group promotes …