Primary Sjögren's syndrome (pSS) is characterized by mononuclear inflammatory infiltrates
and IgG plasma cells in salivary and lacrimal glands which lead to irreversible destruction of …

Protective humoral memory forms in secondary lymphoid organs where B cells undergo
affinity maturation and differentiation into memory or plasma cells. Here, we provide a …

Mast cells (MC) are major participants in the allergic reaction. In addition they possess
immunomodulatory roles in the innate and adaptive immune reactions. Their functions are …

The semaphorin family members were originally considered to play a role in
neurodevelopment, angiogenesis, tumor development, and metastasis. Over the past few …

Background Atherosclerosis, the main underlying pathology of cardiovascular disease, is a
chronic inflammatory disease characterized by lipid accumulation and immune cell …

Hepatitis C cirrhosis is associated with a profound disappearance of memory B-cells. We
sought to determine if this loss is associated with the expansion of the CD27− CD21− tissue …

CD72 is a regulatory co-receptor on B cells, with a role in the pathogenesis of systemic
lupus erythematosus (SLE) in both human and animal models. Semaphorin3A (sema3A) is …

The majority of studies of vaccine responses in Atlantic salmon have focused on several
weeks after vaccination, and employed a limited number of marker genes. In this study …

In vertebrates, the semaphorin family of proteins is composed of 21 members that are
divided into five subfamilies, ie classes 3 to 7. Semaphorins play crucial roles in regulating …

Background. Although neutralizing antibodies play a central role in the control of
cytomegalovirus (CMV) dissemination, little is known about the response of B lymphocytes …