[HTML][HTML] Insight into the binding model of per-and polyfluoroalkyl substances to proteins and membranes

L Zhao, M Teng, X Zhao, Y Li, J Sun, W Zhao… - Environment …, 2023 - Elsevier
Legacy per-and polyfluoroalkyl substances (PFASs) have elicited much concern because of
their ubiquitous distribution in the environment and the potential hazards they pose to …

The EU's per-and Polyfluoroalkyl substances (PFAS) ban: A case of policy over science

F Spyrakis, TA Dragani - Toxics, 2023 - mdpi.com
The proposal by the European Chemicals Agency (ECHA) to ban over 12,000 per-and
polyfluoroalkyl substances (PFAS) has sparked a debate about potential consequences for …

Effects of In Utero PFOS Exposure on Epigenetics and Metabolism in Mouse Fetal Livers

TC Ho, HT Wan, WK Lee, TKY Lam, X Lin… - Environmental …, 2023 - ACS Publications
Prenatal exposure to perfluorooctanesulfonate (PFOS) increases fetus' metabolic risk;
however, the investigation of the underlying mechanism is limited. In this study, pregnant …

[HTML][HTML] Cumulative maternal and neonatal effects of combined exposure to a mixture of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS) …

JM Conley, CS Lambright, N Evans… - Environment …, 2022 - Elsevier
Globally, biomonitoring data demonstrate virtually all humans carry residues of multiple per-
and polyfluoroalkyl substances (PFAS). Despite pervasive co-exposure, limited mixtures …

Association between a Mixture of Per-and Polyfluoroalkyl Substances (PFAS) and Inflammatory Biomarkers in the Atlanta African American Maternal–Child Cohort

Y Tan, KR Taibl, AL Dunlop, DB Barr… - Environmental …, 2023 - ACS Publications
Per-and polyfluoroalkyl substances (PFAS) have been identified as environmental
contributors to adverse birth outcomes. One potential mechanistic pathway could be through …

Transcriptomics integrated with metabolomics reveals perfluorobutane sulfonate (PFBS) exposure effect during pregnancy and lactation on lipid metabolism in rat …

X Meng, G Yu, T Luo, R Zhang, J Zhang, Y Liu - Chemosphere, 2023 - Elsevier
Emerging epidemiological evidence indicates potential associations between gestational
perfluorobutane sulfonate (PFBS) exposure and adverse metabolic outcomes in offspring …

Disclosing environmental ligands of L-FABP and PPARγ: Should we re-evaluate the chemical safety of hydrocarbon surfactants?

Y Gong, D Yang, J Liu, H Barrett, J Sun… - … Science & Technology, 2023 - ACS Publications
Chemical contaminants can cause adverse effects by binding to the liver-fatty acid binding
protein (L-FABP) and peroxisome proliferator-activated nuclear receptor γ (PPARγ), which …

Suspect, nontarget screening, and toxicity prediction of per-and polyfluoroalkyl substances in the landfill leachate

C Feng, Y Lin, S Le, J Ji, Y Chen, G Wang… - Environmental …, 2024 - ACS Publications
Landfills are the final stage of urban wastes containing perfluoroalkyl and polyfluoroalkyl
substances (PFASs). PFASs in the landfill leachate may contaminate the surrounding …

Chemical contaminants in blood and their implications in chronic diseases

Y Zhang, Y Gao, QS Liu, Q Zhou, G Jiang - Journal of Hazardous Materials, 2024 - Elsevier
Artificial chemical products are widely used and ubiquitous worldwide and pose a threat to
the environment and human health. Accumulating epidemiological and toxicological …

Environmental endocrine disruptors and pregnane X receptor action: A review

Y Liang, Y Gong, Q Jiang, Y Yu, J Zhang - Food and Chemical Toxicology, 2023 - Elsevier
The pregnane X receptor (PXR) is a kind of orphan nuclear receptor activated by a series of
ligands. Environmental endocrine disruptors (EEDs) are a wide class of molecules present …