Heterogeneous anomalous transport in cellular and molecular biology
TA Waigh, N Korabel - Reports on Progress in Physics, 2023 - iopscience.iop.org
It is well established that a wide variety of phenomena in cellular and molecular biology
involve anomalous transport eg the statistics for the motility of cells and molecules are …
involve anomalous transport eg the statistics for the motility of cells and molecules are …
[HTML][HTML] The rich inner life of the cell nucleus: dynamic organization, active flows, and emergent rheology
A Zidovska - Biophysical Reviews, 2020 - Springer
The cell nucleus stores the genetic material essential for life, and provides the environment
for transcription, maintenance, and replication of the genome. Moreover, the nucleoplasm is …
for transcription, maintenance, and replication of the genome. Moreover, the nucleoplasm is …
[HTML][HTML] The physics of active polymers and filaments
RG Winkler, G Gompper - The journal of chemical physics, 2020 - pubs.aip.org
Active matter agents consume internal energy or extract energy from the environment for
locomotion and force generation. Already, rather generic models, such as ensembles of …
locomotion and force generation. Already, rather generic models, such as ensembles of …
Polymer folding through active processes recreates features of genome organization
From proteins to chromosomes, polymers fold into specific conformations that control their
biological function. Polymer folding has long been studied with equilibrium thermodynamics …
biological function. Polymer folding has long been studied with equilibrium thermodynamics …
Activity-induced collapse and arrest of active polymer rings
We investigate, using numerical simulations, the conformations of isolated active ring
polymers. We find that their behavior depends crucially on their size: Short rings (N≲ 100) …
polymers. We find that their behavior depends crucially on their size: Short rings (N≲ 100) …
Self-Organized States from Solutions of Active Ring Polymers in Bulk and under Confinement
JP Miranda, E Locatelli, C Valeriani - Journal of Chemical Theory …, 2023 - ACS Publications
In the present work, we study, by means of numerical simulations, the structural and
dynamical behavior of a suspension of active ring polymers in bulk and under lateral …
dynamical behavior of a suspension of active ring polymers in bulk and under lateral …
Euchromatin activity enhances segregation and compaction of heterochromatin in the cell nucleus
The large-scale organization of the genome inside the cell nucleus is critical for the cell's
function. Chromatin—the functional form of DNA in cells—serves as a template for active …
function. Chromatin—the functional form of DNA in cells—serves as a template for active …
Tangentially driven active polar linear polymers—An analytical study
CA Philipps, G Gompper, RG Winkler - The Journal of Chemical …, 2022 - pubs.aip.org
The conformational and dynamical properties of isolated flexible active polar linear polymers
(APLPs) are studied analytically. The APLPs are modeled as Gaussian bead-spring linear …
(APLPs) are studied analytically. The APLPs are modeled as Gaussian bead-spring linear …
The scales, mechanisms, and dynamics of the genome architecture
L Lizana, YB Schwartz - Science Advances, 2024 - science.org
Even when split into several chromosomes, DNA molecules that make up our genome are
too long to fit into the cell nuclei unless massively folded. Such folding must accommodate …
too long to fit into the cell nuclei unless massively folded. Such folding must accommodate …
Harnessing the power of chemically active sheets in solution
In living organisms, diffusing chemicals react with soft tissue to actuate a range of
mechanical actions, such as periodic pulsations or net motion. Inspired by this biological …
mechanical actions, such as periodic pulsations or net motion. Inspired by this biological …