Deconvolution of serum cortisol levels by using compressed sensing
The pulsatile release of cortisol from the adrenal glands is controlled by a hierarchical
system that involves corticotropin releasing hormone (CRH) from the hypothalamus …
system that involves corticotropin releasing hormone (CRH) from the hypothalamus …
Characterization of cortisol dysregulation in fibromyalgia and chronic fatigue syndromes: a state-space approach
Objective: Fibromyalgia syndrome (FMS) and chronic fatigue syndrome (CFS) are
complicated medical disorders, with little known etiologies. The purpose of this research is to …
complicated medical disorders, with little known etiologies. The purpose of this research is to …
Mathematical modeling of light-mediated HPA axis activity and downstream implications on the entrainment of peripheral clock genes
PD Mavroudis, SA Corbett, SE Calvano… - Physiological …, 2014 - journals.physiology.org
In this work we propose a semimechanistic model that describes the photic signal
transduction to the hypothalamic-pituitary-adrenal (HPA) axis that ultimately regulates the …
transduction to the hypothalamic-pituitary-adrenal (HPA) axis that ultimately regulates the …
From physiological signals to pulsatile dynamics: a sparse system identification approach
RT Faghih - Dynamic Neuroscience: Statistics, Modeling, and …, 2018 - Springer
Various brain signals including neuronal spiking activity have an impulsive profile that upon
interactions with physiological or measurement processes lead to observed pulsatile …
interactions with physiological or measurement processes lead to observed pulsatile …
Modeling and control of pharmacodynamics
CL Beck - European Journal of Control, 2015 - Elsevier
Modeling and control of drug dosing regimes are particularly well-suited for applications of
control design and analysis techniques. These problems frequently incorporate the use of …
control design and analysis techniques. These problems frequently incorporate the use of …
A system theoretic investigation of cortisol dysregulation in fibromyalgia patients with chronic fatigue
Fibromyalgia Syndrome (FMS) and Chronic Fatigue Syndrome (CFS) are complex medical
conditions with similar symptoms such as anxiety, fatigue, depression, headaches, muscle …
conditions with similar symptoms such as anxiety, fatigue, depression, headaches, muscle …
Novel regulation mechanism of adrenal cortisol and DHEA biosynthesis via the endogen ERAD inhibitor small VCP-interacting protein
Endoplasmic reticulum-associated degradation (ERAD) is a well-characterized mechanism
of protein quality control by removal of misfolded or unfolded proteins. The tight regulation of …
of protein quality control by removal of misfolded or unfolded proteins. The tight regulation of …
Quantifying pituitary-adrenal dynamics and deconvolution of concurrent cortisol and adrenocorticotropic hormone data by compressed sensing
Pulsatile release of cortisol from the adrenal glands is governed by pulsatile release of
adrenocorticotropic hormone (ACTH) from the anterior pituitary. In return, cortisol has a …
adrenocorticotropic hormone (ACTH) from the anterior pituitary. In return, cortisol has a …
A wearable brain machine interface architecture for regulation of energy in hypercortisolism
Hypercortisolism is associated with tiredness and fatigue during the day and disturbed sleep
at night. Our goal is to employ a wearable brain machine interface architecture to regulate …
at night. Our goal is to employ a wearable brain machine interface architecture to regulate …
An optimization formulation for characterization of pulsatile cortisol secretion
Cortisol is released to relay information to cells to regulate metabolism and reaction to stress
and inflammation. In particular, cortisol is released in the form of pulsatile signals. This low …
and inflammation. In particular, cortisol is released in the form of pulsatile signals. This low …