Systemic amyloidosis from A (AA) to T (ATTR): a review

E Muchtar, A Dispenzieri, H Magen… - Journal of internal …, 2021 - Wiley Online Library
Systemic amyloidosis is a rare protein misfolding and deposition disorder leading to
progressive organ failure. There are over 15 types of systemic amyloidosis, each caused by …

[HTML][HTML] RNA targeting and gene editing strategies for transthyretin amyloidosis

A Ioannou, M Fontana, JD Gillmore - BioDrugs, 2023 - Springer
Transthyretin (TTR) is a tetrameric protein synthesized primarily by the liver. TTR can misfold
into pathogenic ATTR amyloid fibrils that deposit in the nerves and heart, causing a …

[HTML][HTML] Procedural recommendations of cardiac PET/CT imaging: standardization in inflammatory-, infective-, infiltrative-, and innervation (4Is)-related cardiovascular …

RHJA Slart, AWJM Glaudemans, O Gheysens… - European journal of …, 2021 - Springer
With this document, we provide a standard for PET/(diagnostic) CT imaging procedures in
cardiovascular diseases that are inflammatory, infective, infiltrative, or associated with …

[18F]-florbetaben PET/CT for differential diagnosis among cardiac immunoglobulin light chain, transthyretin amyloidosis, and mimicking conditions

D Genovesi, G Vergaro, A Giorgetti, P Marzullo… - Cardiovascular …, 2021 - jacc.org
Objectives This study aimed to test the diagnostic value of [18F]–florbetaben positron
emission tomography (PET) in patients with suspicion of CA. Background Diagnosis of …

Visualization of fibroblast activation after myocardial infarction using 68Ga-FAPI PET

L Kessler, J Kupusovic, J Ferdinandus… - Clinical Nuclear …, 2021 - journals.lww.com
Aims The aim of this retrospective analysis was to examine the pattern of cardiac 68 Ga-
fibroblast-activation protein-α inhibitor (FAPI) uptake in patients after acute myocardial …

[HTML][HTML] Association of MRI-derived radiomic biomarker with disease-free survival in patients with early-stage cervical cancer

J Fang, B Zhang, S Wang, Y Jin, F Wang, Y Ding… - Theranostics, 2020 - ncbi.nlm.nih.gov
Pre-treatment survival prediction plays a key role in many diseases. We aimed to determine
the prognostic value of pre-treatment Magnetic Resonance Imaging (MRI) based radiomic …

Cardiac amyloidosis and aortic stenosis: a state-of-the-art review

V Jaiswal, V Agrawal, Y Khulbe, M Hanif… - … Heart Journal Open, 2023 - academic.oup.com
Cardiac amyloidosis is caused by the extracellular deposition of amyloid fibrils in the heart,
involving not only the myocardium but also any cardiovascular structure. Indeed, this …

[HTML][HTML] Positron emission tomography in the diagnosis and follow-up of transthyretin amyloid cardiomyopathy patients: a systematic review

HSA Tingen, A Tubben, JH Van'T Oever… - European journal of …, 2023 - Springer
Purpose Transthyretin (ATTR) amyloidosis is a progressive protein misfolding disease with
frequent cardiac involvement. This review aims to determine the value of PET in diagnosis …

Cardiac amyloidosis: multimodal imaging of disease activity and response to treatment

RK Patel, M Fontana, FL Ruberg - Circulation: Cardiovascular …, 2021 - Am Heart Assoc
Cardiac amyloidosis (CA) is a disease characterized by the deposition of misfolded protein
deposits in the myocardial interstitium. Although advanced CA confers significant morbidity …

[HTML][HTML] Characterizing cardiac involvement in amyloidosis using cardiovascular magnetic resonance diffusion tensor imaging

A Gotschy, C von Deuster, RJH van Gorkum… - Journal of …, 2019 - Springer
Background In-vivo cardiovascular magnetic resonance (CMR) diffusion tensor imaging
(DTI) allows imaging of alterations of cardiac fiber architecture in diseased hearts. Cardiac …