Integrating machine learning and multiscale modeling—perspectives, challenges, and opportunities in the biological, biomedical, and behavioral sciences

M Alber, A Buganza Tepole, WR Cannon, S De… - NPJ digital …, 2019 - nature.com
Fueled by breakthrough technology developments, the biological, biomedical, and
behavioral sciences are now collecting more data than ever before. There is a critical need …

[HTML][HTML] Machine learning in healthcare

H Habehh, S Gohel - Current genomics, 2021 - ncbi.nlm.nih.gov
Abstract Recent advancements in Artificial Intelligence (AI) and Machine Learning (ML)
technology have brought on substantial strides in predicting and identifying health …

The promise of machine learning in predicting treatment outcomes in psychiatry

AM Chekroud, J Bondar, J Delgadillo… - World …, 2021 - Wiley Online Library
For many years, psychiatrists have tried to understand factors involved in response to
medications or psychotherapies, in order to personalize their treatment choices. There is …

Causal machine learning for healthcare and precision medicine

P Sanchez, JP Voisey, T Xia… - Royal Society …, 2022 - royalsocietypublishing.org
Causal machine learning (CML) has experienced increasing popularity in healthcare.
Beyond the inherent capabilities of adding domain knowledge into learning systems, CML …

Multiscale modeling meets machine learning: What can we learn?

GCY Peng, M Alber, A Buganza Tepole… - … Methods in Engineering, 2021 - Springer
Abstract Machine learning is increasingly recognized as a promising technology in the
biological, biomedical, and behavioral sciences. There can be no argument that this …

From real‐world patient data to individualized treatment effects using machine learning: current and future methods to address underlying challenges

I Bica, AM Alaa, C Lambert… - Clinical Pharmacology …, 2021 - Wiley Online Library
Clinical decision making needs to be supported by evidence that treatments are beneficial to
individual patients. Although randomized control trials (RCTs) are the gold standard for …

Artificial intelligence for precision medicine in neurodevelopmental disorders

M Uddin, Y Wang, M Woodbury-Smith - NPJ digital medicine, 2019 - nature.com
The ambition of precision medicine is to design and optimize the pathway for diagnosis,
therapeutic intervention, and prognosis by using large multidimensional biological datasets …

The state of our understanding of the pathophysiology and optimal treatment of depression: glass half full or half empty?

CB Nemeroff - American Journal of Psychiatry, 2020 - Am Psychiatric Assoc
Major depressive disorder is a remarkably common and often severe psychiatric disorder
associated with high levels of morbidity and mortality. Patients with major depression are …

[HTML][HTML] Supervised machine learning in drug discovery and development: Algorithms, applications, challenges, and prospects

G Obaido, ID Mienye, OF Egbelowo… - Machine Learning with …, 2024 - Elsevier
Drug discovery and development is a time-consuming process that involves identifying,
designing, and testing new drugs to address critical medical needs. In recent years, machine …

Machine learning in the prediction of depression treatment outcomes: a systematic review and meta-analysis

M Sajjadian, RW Lam, R Milev, S Rotzinger… - Psychological …, 2021 - cambridge.org
Background Multiple treatments are effective for major depressive disorder (MDD), but the
outcomes of each treatment vary broadly among individuals. Accurate prediction of …