Role of hemodynamic shear stress in cardiovascular disease

E Cecchi, C Giglioli, S Valente, C Lazzeri, GF Gensini… - Atherosclerosis, 2011 - Elsevier
Atherosclerosis is the main cause of morbidity and mortality in the Western world.
Inflammation and blood flow alterations are new markers emerging as possible …

Biology of intracranial aneurysms: role of inflammation

N Chalouhi, MS Ali, PM Jabbour… - Journal of Cerebral …, 2012 - journals.sagepub.com
Intracranial aneurysms (IAs) linger as a potentially devastating clinical problem. Despite
intense investigation, our understanding of the mechanisms leading to aneurysm …

Hemodynamic–morphologic discriminants for intracranial aneurysm rupture

J Xiang, SK Natarajan, M Tremmel, D Ma, J Mocco… - Stroke, 2011 - Am Heart Assoc
Background and Purpose—The purpose of this study was to identify significant
morphological and hemodynamic parameters that discriminate intracranial aneurysm …

Prediction of 3D Cardiovascular hemodynamics before and after coronary artery bypass surgery via deep learning

G Li, H Wang, M Zhang, S Tupin, A Qiao, Y Liu… - Communications …, 2021 - nature.com
The clinical treatment planning of coronary heart disease requires hemodynamic
parameters to provide proper guidance. Computational fluid dynamics (CFD) is gradually …

Morphology parameters for intracranial aneurysm rupture risk assessment

S Dhar, M Tremmel, J Mocco, M Kim, J Yamamoto… - …, 2008 - journals.lww.com
OBJECTIVE: The aim of this study is to identify image-based morphological parameters that
correlate with human intracranial aneurysm (IA) rupture. METHODS: For 45 patients with …

Complex hemodynamics at the apex of an arterial bifurcation induces vascular remodeling resembling cerebral aneurysm initiation

H Meng, Z Wang, Y Hoi, L Gao, E Metaxa, DD Swartz… - Stroke, 2007 - Am Heart Assoc
Background and Purpose—Arterial bifurcation apices are common sites for cerebral
aneurysms, raising the possibility that the unique hemodynamic conditions associated with …

[HTML][HTML] CFD investigations of the blood hemodynamic inside internal cerebral aneurysm (ICA) in the existence of coiling embolism

ZH Jin, MB Gerdroodbary, P Valipour, M Faraji… - Alexandria Engineering …, 2023 - Elsevier
The coiling technique is the most significant and conventional option for treating an
intracranial aneurysm. Besides, the effects of blood hemodynamics are also known as the …

A framework for geometric analysis of vascular structures: application to cerebral aneurysms

M Piccinelli, A Veneziani, DA Steinman… - IEEE transactions on …, 2009 - ieeexplore.ieee.org
There is well-documented evidence that vascular geometry has a major impact in blood flow
dynamics and consequently in the development of vascular diseases, like atherosclerosis …

The critical role of hemodynamics in the development of cerebral vascular disease: a review

AM Nixon, M Gunel, BE Sumpio - Journal of neurosurgery, 2010 - thejns.org
Atherosclerosis and intracranial saccular aneurysms predictably localize in areas with
complex arterial geometries such as bifurcations and curvatures. These sites are …

Intracranial and abdominal aortic aneurysms: similarities, differences, and need for a new class of computational models

JD Humphrey, CA Taylor - Annu. Rev. Biomed. Eng., 2008 - annualreviews.org
Intracranial saccular and abdominal aortic aneurysms (ISAs and AAAs, respectively) result
from different underlying disease processes and exhibit different rupture potentials, yet they …