ROS‐mediated cancer cell killing through dietary phytochemicals

S NavaneethaKrishnan, JL Rosales… - Oxidative medicine and …, 2019 - Wiley Online Library
Reactive oxygen species (ROS) promote carcinogenesis by inducing genetic mutations,
activating oncogenes, and raising oxidative stress, which all influence cell proliferation …

Apoptosis induction of fibroblast-like synoviocytes is an important molecular-mechanism for herbal medicine along with its active components in treating rheumatoid …

Q Zhang, J Liu, M Zhang, S Wei, R Li, Y Gao, W Peng… - Biomolecules, 2019 - mdpi.com
Rheumatoid arthritis (RA) is a known chronic autoimmune disease can cause joint deformity
and even loss of joint function. Fibroblast-like synoviocytes (FLS), one of the main cell types …

Interaction of dietary polyphenols with bovine milk proteins: Molecular structure–affinity relationship and influencing bioactivity aspects

J Xiao, F Mao, F Yang, Y Zhao, C Zhang… - Molecular nutrition & …, 2011 - Wiley Online Library
Scope: Dietary flavonoids and stilbenes are important polyphenols in foods, such as, eg
fruits, vegetables, nuts, and tea as they are of great interest for their bioactivities, which are …

Metal nanoparticles synthesis through natural phenolic acids

SM Amini, A Akbari - IET nanobiotechnology, 2019 - Wiley Online Library
For being applied in medicine as therapeutic agents, nanostructures need to be
biocompatible and eco‐friendly. Plant‐derived phenolic acids have been utilised for green …

Inhibition of melanogenesis by gallic acid: Possible involvement of the PI3K/Akt, MEK/ERK and Wnt/β-catenin signaling pathways in B16F10 cells

TR Su, JJ Lin, CC Tsai, TK Huang, ZY Yang… - International journal of …, 2013 - mdpi.com
Gallic acid is one of the major flavonoids found in plants. It acts as an antioxidant, and
seems to have anti-inflammatory, anti-viral, and anti-cancer properties. In this study, we …

Green synthesis of gallic acid-coated silver nanoparticles with high antimicrobial activity and low cytotoxicity to normal cells

D Li, Z Liu, Y Yuan, Y Liu, F Niu - Process Biochemistry, 2015 - Elsevier
Antibiotic resistance creates a challenge for developing new drugs to overcome infections.
Silver nanoparticles (AgNPs) have become an attractive alternative to antibiotics due to their …

p53: a key protein that regulates pulmonary fibrosis

Q Wu, K Zhang, S Jiang, L Fu, Y Shi… - Oxidative Medicine …, 2020 - Wiley Online Library
Pulmonary fibrosis is a progressively aggravating lethal disease that is a serious public
health concern. Although the incidence of this disease is increasing, there is a lack of …

Gallic acid induces apoptosis and enhances the anticancer effects of cisplatin in human small cell lung cancer H446 cell line via the ROS-dependent mitochondrial …

R Wang, L Ma, D Weng, J Yao, X Liu… - Oncology …, 2016 - spandidos-publications.com
Small cell lung cancer (SCLC) is the most aggressive lung cancer subtype and accounts for
more than 15% of all lung cancer cases. Cisplatin [cis-diamminedichloroplatinum (CDDP)] …

Gallic acid: A dietary polyphenol that exhibits anti-neoplastic activities by modulating multiple oncogenic targets

HS Tuli, H Mistry, G Kaur, D Aggarwal… - Anti-Cancer Agents …, 2022 - ingentaconnect.com
Phytochemicals are being used for thousands of years to prevent dreadful malignancy. Side
effects of existing allopathic treatment have also initiated intense research in the field of …

p53 and myofibroblast apoptosis in organ fibrosis

K McElhinney, M Irnaten, C O'Brien - International Journal of Molecular …, 2023 - mdpi.com
Organ fibrosis represents a dysregulated, maladaptive wound repair response that results in
progressive disruption of normal tissue architecture leading to detrimental deterioration in …