[HTML][HTML] Solving the time-dependent protein distributions for autoregulated bursty gene expression using spectral decomposition

B Wu, J Holehouse, R Grima, C Jia - The Journal of Chemical Physics, 2024 - pubs.aip.org
In this study, we obtain an exact time-dependent solution of the chemical master equation
(CME) of an extension of the two-state telegraph model describing bursty or non-bursty …

First passage on disordered intervals

J Holehouse, S Redner - Physical Review E, 2024 - APS
We derive unexpected first-passage properties for nearest-neighbor hopping on finite
intervals with disordered hopping rates, including (a) a highly variable spatial dependence …

Nonequilibrium dynamics of the Ising model on heterogeneous networks with an arbitrary distribution of threshold noise

LS Ferreira, FL Metz - Physical Review E, 2023 - APS
The Ising model on networks plays a fundamental role as a testing ground for understanding
cooperative phenomena in complex systems. Here we solve the synchronous dynamics of …

Recurrence and Eigenfunction Methods for Non-Trivial Models of Discrete Binary Choice

J Holehouse - Entropy, 2023 - mdpi.com
Understanding how systems relax to equilibrium is a core theme of statistical physics,
especially in economics, where systems are known to be subject to extrinsic noise not …

A binary decision model and fat tails in financial market

K Sano - Applied Sciences, 2022 - mdpi.com
Binary decision models have been the subject of renewed research in recent years. In these
models, agents follow a stochastic evolution where they must choose between two possible …

Quasi-critical dynamics in large-scale social systems regulated by sudden events

P Guo, Y Xu, S Guo, Y Tian, P Sun - Chaos: An Interdisciplinary Journal …, 2024 - pubs.aip.org
How do heterogeneous individual behaviors arise in response to sudden events and how
do they shape large-scale social dynamics? Based on a five-year naturalistic observation of …

Principles of bursty mRNA expression and irreversibility in single cells and extrinsically varying populations

J Holehouse - arXiv preprint arXiv:2405.12897, 2024 - arxiv.org
The canonical model of mRNA expression is the telegraph model, describing a gene that
switches on and off, subject to transcription and decay. It describes steady-state mRNA …

Closed-form solution of a general three-term recurrence relation: applications to Heun functions and social choice models

J Holehouse - arXiv preprint arXiv:2302.04187, 2023 - arxiv.org
We derive a concise closed-form solution for a linear three-term recurrence relation. Such
recurrence relations are very common in the quantitative sciences, and describe finite …