[HTML][HTML] The immune response to SARS-CoV-2 and COVID-19 immunopathology–Current perspectives

JL Boechat, I Chora, A Morais, L Delgado - Pulmonology, 2021 - Elsevier
SARS-CoV-2 is a new beta coronavirus, similar to SARS-CoV-1, that emerged at the end of
2019 in the Hubei province of China. It is responsible for coronavirus disease 2019 (COVID …

COVID‐19: immunopathology, pathophysiological mechanisms, and treatment options

LE van Eijk, M Binkhorst, AR Bourgonje… - The Journal of …, 2021 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS‐CoV‐2), continues to spread globally despite the worldwide …

Molecular Docking and Dynamics Simulation Revealed the Potential Inhibitory Activity of ACEIs Against SARS-CoV-2 Targeting the hACE2 Receptor

AA Al-Karmalawy, MA Dahab, AM Metwaly… - Frontiers in …, 2021 - frontiersin.org
The rapid and global spread of a new human coronavirus, Severe Acute Respiratory
Syndrome Coronavirus 2 (SARS-CoV-2) has produced an immediate urgency to discover …

No evidence for basigin/CD147 as a direct SARS-CoV-2 spike binding receptor

J Shilts, TWM Crozier, EJD Greenwood, PJ Lehner… - Scientific reports, 2021 - nature.com
The spike protein of SARS-CoV-2 is known to enable viral invasion into human cells through
direct binding to host receptors including ACE2. An alternate entry receptor for the virus was …

[HTML][HTML] Calendulaglycoside A showing potential activity against SARS-CoV-2 main protease: Molecular docking, molecular dynamics, and SAR studies

AA Zaki, A Ashour, SS Elhady, KM Darwish… - Journal of traditional and …, 2022 - Elsevier
Background and aim The discovery of drugs capable of inhibiting SARS-CoV-2 is a priority
for human beings due to the severity of the global health pandemic caused by COVID-19. To …

SARS-CoV-2 cell entry beyond the ACE2 receptor

SD Alipoor, M Mirsaeidi - Molecular biology reports, 2022 - Springer
Background Angiotensin-converting enzyme 2 (ACE2) is known as the major viral entry site
for SARS-CoV-2. However, viral tissue tropism and high rate of infectivity do not directly …

In a search for potential drug candidates for combating COVID-19: computational study revealed salvianolic acid B as a potential therapeutic targeting 3CLpro and …

AA Elmaaty, KM Darwish, M Khattab… - Journal of …, 2022 - Taylor & Francis
The global prevalence of COVID-19 disease and the overwhelming increase in death toll
urge scientists to discover new effective drugs. Although the drug discovery process is a …

An update on the pathogenesis of COVID-19 and the reportedly rare thrombotic events following vaccination

B Kantarcioglu, O Iqbal, JM Walenga… - Clinical and Applied …, 2021 - journals.sagepub.com
Today the coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus-2 (SARS-CoV-2), has become a global health problem. After more …

Cellular mechanisms underlying neurological/neuropsychiatric manifestations of COVID‐19

B Bodnar, K Patel, W Ho, JJ Luo… - Journal of Medical …, 2021 - Wiley Online Library
Patients with severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) infection
manifest mainly respiratory symptoms. However, clinical observations frequently identified …

Exploring the role of immune system and inflammatory cytokines in SARS-CoV-2 induced lung disease: a narrative review

C Tirelli, M De Amici, C Albrici, S Mira, G Nalesso, B Re… - Biology, 2023 - mdpi.com
Simple Summary Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
responsible for the pandemic coronavirus disease-2019 (COVID-19), which can lead to …