Switch and trace: recombinase genetics in zebrafish
TJ Carney, C Mosimann - Trends in Genetics, 2018 - cell.com
Transgenic approaches are instrumental for labeling and manipulating cells and cellular
machineries in vivo. Transgenes have traditionally been static entities that remained …
machineries in vivo. Transgenes have traditionally been static entities that remained …
Transient fibrosis resolves via fibroblast inactivation in the regenerating zebrafish heart
H Sánchez-Iranzo, M Galardi-Castilla… - Proceedings of the …, 2018 - National Acad Sciences
In the zebrafish (Danio rerio), regeneration and fibrosis after cardiac injury are not mutually
exclusive responses. Upon cardiac cryoinjury, collagen and other extracellular matrix (ECM) …
exclusive responses. Upon cardiac cryoinjury, collagen and other extracellular matrix (ECM) …
Refined protocols of tamoxifen injection for inducible DNA recombination in mouse astroglia
HM Jahn, CV Kasakow, A Helfer, J Michely… - Scientific reports, 2018 - nature.com
Inducible DNA recombination of floxed alleles in vivo by liver metabolites of tamoxifen (TAM)
is an important tool to study gene functions. Here, we describe protocols for optimal DNA …
is an important tool to study gene functions. Here, we describe protocols for optimal DNA …
pIGLET: Safe harbor landing sites for reproducible and efficient transgenesis in zebrafish
RL Lalonde, HH Wells, CL Kemmler… - Science …, 2024 - science.org
Standard zebrafish transgenesis involves random transgene integration with resource-
intensive screening. While phiC31 integrase–based attP/attB recombination has streamlined …
intensive screening. While phiC31 integrase–based attP/attB recombination has streamlined …
Tbx5a lineage tracing shows cardiomyocyte plasticity during zebrafish heart regeneration
H Sánchez-Iranzo, M Galardi-Castilla… - Nature …, 2018 - nature.com
During development, mesodermal progenitors from the first heart field (FHF) form a primitive
cardiac tube, to which progenitors from the second heart field (SHF) are added. The …
cardiac tube, to which progenitors from the second heart field (SHF) are added. The …
Continuous addition of progenitors forms the cardiac ventricle in zebrafish
A Felker, KD Prummel, AM Merks, M Mickoleit… - Nature …, 2018 - nature.com
The vertebrate heart develops from several progenitor lineages. After early-differentiating
first heart field (FHF) progenitors form the linear heart tube, late-differentiating second heart …
first heart field (FHF) progenitors form the linear heart tube, late-differentiating second heart …
Limitations of Tamoxifen Application for In Vivo Genome Editing Using Cre/ERT2 System
LA Ilchuk, NI Stavskaya, EA Varlamova… - International Journal of …, 2022 - mdpi.com
Inducible Cre-dependent systems are frequently used to produce both conditional knockouts
and transgenic mice with regulated expression of the gene of interest. Induction can be …
and transgenic mice with regulated expression of the gene of interest. Induction can be …
Dermal appendage-dependent patterning of zebrafish atoh1a+ Merkel cells
TL Brown, EC Horton, EW Craig, CEA Goo, EC Black… - Elife, 2023 - elifesciences.org
Touch system function requires precise interactions between specialized skin cells and
somatosensory axons, as exemplified by the vertebrate mechanosensory Merkel cell-neurite …
somatosensory axons, as exemplified by the vertebrate mechanosensory Merkel cell-neurite …
[HTML][HTML] Adult sox10+ cardiomyocytes contribute to myocardial regeneration in the zebrafish
M Sande-Melon, IJ Marques, M Galardi-Castilla… - Cell reports, 2019 - cell.com
During heart regeneration in the zebrafish, fibrotic tissue is replaced by newly formed
cardiomyocytes derived from preexisting ones. It is unclear whether the heart is composed of …
cardiomyocytes derived from preexisting ones. It is unclear whether the heart is composed of …
Hand2 delineates mesothelium progenitors and is reactivated in mesothelioma
The mesothelium lines body cavities and surrounds internal organs, widely contributing to
homeostasis and regeneration. Mesothelium disruptions cause visceral anomalies and …
homeostasis and regeneration. Mesothelium disruptions cause visceral anomalies and …