Genotyping and interpretation of STR-DNA: low-template, mixtures and database matches—twenty years of research and development

P Gill, H Haned, O Bleka, O Hansson, G Dørum… - Forensic Science …, 2015 - Elsevier
Abstract The introduction of Short Tandem Repeat (STR) DNA was a revolution within a
revolution that transformed forensic DNA profiling into a tool that could be used, for the first …

Statistical evaluation of forensic DNA profile evidence

CD Steele, DJ Balding - Annual Review of Statistics and Its …, 2014 - annualreviews.org
The evaluation of weight of evidence for forensic DNA profiles has been a subject of
controversy since their introduction over 20 years ago. Substantial progress has been made …

[图书][B] Weight-of-evidence for Forensic DNA Profiles

DJ Balding, CD Steele - 2015 - books.google.com
DNA evidence is widely used in the modern justice system. Statistical methodology plays a
key role in ensuring that this evidence is collected, interpreted, analysed and presented …

Analysis of forensic DNA mixtures with artefacts

RG Cowell, T Graversen, SL Lauritzen… - Journal of the Royal …, 2015 - academic.oup.com
DNA is now routinely used in criminal investigations and court cases, although DNA
samples taken at crime scenes are of varying quality and therefore present challenging …

Evaluating forensic DNA profiles using peak heights, allowing for multiple donors, allelic dropout and stutters

R Puch-Solis, L Rodgers, A Mazumder, S Pope… - Forensic Science …, 2013 - Elsevier
Increases in the sensitivity of DNA profiling technology now allow profiles to be obtained
from smaller and more degraded DNA samples than was previously possible. The resulting …

Statistical model for degraded DNA samples and adjusted probabilities for allelic drop-out

T Tvedebrink, PS Eriksen, HS Mogensen… - Forensic Science …, 2012 - Elsevier
DNA samples found at a scene of crime or obtained from the debris of a mass disaster
accident are often subject to degradation. When using the STR DNA technology, the DNA …

[HTML][HTML] Limitations of qPCR to estimate DNA quantity: An RFU method to facilitate inter-laboratory comparisons for activity level, and general applicability

P Gill, Ø Bleka, AE Fonneløp - Forensic Science International: Genetics, 2022 - Elsevier
The application of qPCR to estimate the quantity of DNA present is usually based upon a
short amplicon (typically c. 80bp) and a longer amplicon (typically c. 200–300bp) where the …

Understanding the characteristics of sequence-based single-source DNA profiles

S Riman, H Iyer, LA Borsuk, PM Vallone - Forensic Science International …, 2020 - Elsevier
The sequencing of STR markers provides additional information present in the underlying
sequence variation that is typically masked by traditional fragment-based genotyping …

DNA profiling methods and tools: A review

E Alamoudi, R Mehmood, A Albeshri… - … and Applications: First …, 2018 - Springer
DNA typing or profiling is a widely used practice in various forensic laboratories, used, for
example, in sexual assault cases when the source of DNA mixture can combine different …

Overdispersion in allelic counts and θ-correction in forensic genetics

T Tvedebrink - Theoretical population biology, 2010 - Elsevier
We present a statistical model for incorporating the extra variability in allelic counts due to
subpopulation structures. In forensic genetics, this effect is modelled by the identical-by …