BPA is one of the most common endocrine disruptors that is widely being manufactured
daily nationwide. Although scientific evidence supports claims of negative effects of BPA on …

Phthalates and bisphenols are high production volume chemicals that are used in the
manufacturing of consumer and medical products. Given the ubiquity of bisphenol and …

Endocrine-disrupting chemicals (EDC) are a wide group of chemicals that interfere with the
endocrine system. Their similarity to natural steroid hormones makes them able to attach to …

Background: The concept of chemical agents having properties that confer potential hazard
called key characteristics (KCs) was first developed to identify carcinogenic hazards …

Pyriproxyfen (PPF), a well-known synthetic substance, acts as an analog of juvenile insect
hormone and is persistently used as insecticides as well as larvicides across the globe. At …

Bisphenol A (BPA; 4, 4′-isopropylidenediphenol) is a well-known endocrine disruptor. Most
human exposure to BPA occurs through the consumption of BPA-contaminated foods …

Bisphenol AF (BPAF), a kind of the ideal substitutes of Bisphenol A (BPA), has frequently
been detected in environmental media and biological samples. Numerous studies have …

microRNAs (miRNAs) are susceptible to environmental factors that might affect cellular
function and impose negative effects on female reproduction. miR-21 is the most abundant …

Circular RNAs (circRNAs) are a novel type of long non-coding RNAs that can regulate gene
expression in heart development and heart disease. However, the expression pattern of …

Abstract Background Bisphenol A (BPA), a common endocrine-disrupting chemical (EDC),
has been revealed to be closely associated with the induction of abnormal heart …