Hemorrhage is one of the most significant effects in envenomings induced by viperid
snakebites. Damage to the microvasculature, induced by snake venom metalloproteinases …

Snake venom proteins that affect the haemostatic system can cause (a) lowering of blood
coagulability,(b) damage to blood vessels, resulting in bleeding,(c) secondary effects of …

We describe two geographically differentiated venom phenotypes across the wide
distribution range of Bothrops atrox, from the Colombian Magdalena Medio Valley through …

Many active secretions produced by animals have been employed in the development of
new drugs to treat diseases such as hypertension and cancer. Snake venom toxins …

Bothrops atrox snakes are mostly endemic of the Amazon rainforest and is certainly the
South American pit viper responsible for most of the snakebites in the region. The …

Background Multifunctional l-amino acid oxidases (LAAOs) occur widely in snake venoms.
Methods The l-AAO from Bothrops leucurus (Bl-LAAO) venom was purified using a …

Snake envenoming represents a major burden for public health worldwide. In the Amazon,
the official number of cases and deaths detected is probably underestimated because of the …

Elucidating the molecular mechanisms underlying snake venom variability provides
important clues for understanding how the biological functions of this powerful toxic arsenal …

Venom variability is commonly reported for venomous snakes including Bothrops atrox.
Here, we compared the composition of venoms from B. atrox snakes collected at Amazonian …

The clinical manifestations of Bothrops atrox envenoming involve local and systemic
changes, among which edema requires substantial attention due to its ability to progress to …