Flavonoids as promising neuroprotectants and their therapeutic potential against Alzheimer's disease

T Minocha, H Birla, AA Obaid, V Rai… - Oxidative Medicine …, 2022 - Wiley Online Library
Alzheimer's disease (AD) is one of the serious and progressive neurodegenerative
disorders in the elderly worldwide. Various genetic, environmental, and lifestyle factors are …

Bioactive compounds of the Mediterranean diet as nutritional support to fight neurodegenerative disease

GA Franco, L Interdonato, M Cordaro… - International Journal of …, 2023 - mdpi.com
Neurodegenerative disorders are a widespread cause of morbidity and mortality worldwide,
characterized by neuroinflammation, oxidative stress, and neuronal depletion. They include …

[HTML][HTML] Natural and semi-synthetic flavonoid anti-SARS-CoV-2 agents for the treatment of long COVID-19 disease and neurodegenerative disorders of cognitive …

J Melrose, MM Smith - Frontiers in Bioscience-Elite, 2022 - imrpress.com
The aim of this review is to highlight the beneficial attributes of flavonoids, a diverse family of
widely-distributed polyphenolic phytochemicals that have beneficial cell and tissue …

Does hazelnut consumption affect brain health and function against neurodegenerative diseases?

S Talebi, F Khodagholi, Z Bahaeddin… - Nutritional …, 2024 - Taylor & Francis
Introduction: A healthy daily diet and consuming certain nutrients, such as polyphenols,
vitamins, and unsaturated fatty acids, may help neuronal health maintenance. Polyphenolic …

Recent Development of Novel Aminoethyl-Substituted Chalcones as Potential Drug Candidates for the Treatment of Alzheimer's Disease

P Sharma, M Singh, V Singh, TG Singh, T Singh… - Molecules, 2023 - mdpi.com
No drug on the market, as a single entity, participates in different pathways involved in the
pathology of Alzheimer's disease. The current study is aimed at the exploration of …

Mangifera indica 'Namdokmai' Prevents Neuronal Cells from Amyloid Peptide Toxicity and Inhibits BACE-1 Activities in a Drosophila Model of Alzheimer's …

P Temviriyanukul, S Kittibunchakul, P Trisonthi… - Pharmaceuticals, 2022 - mdpi.com
Alzheimer's disease (AD) is a progressive neurological illness with few effective treatments.
Thus, ameliorating the effects of AD using natural products has attracted global attention …

Dietary flavonoids modulate the gut microbiota: A new perspective on improving autism spectrum disorder through the gut-brain axis

H Dai, Y Jiang, S Liu, D Li, X Zhang - Food Research International, 2024 - Elsevier
Autism spectrum disorder (ASD) is a neurodevelopmental disorder with an unknown
etiology. It is associated with various factors and causes great inconvenience to the patient's …

5, 7-dihydroxy-3′, 4′, 5′-trimethoxyflavone mitigates lead induced neurotoxicity in rats via its chelating, antioxidant, anti-inflammatory and monoaminergic …

V Singh, R Shri, P Sood, M Singh, TG Singh… - Food and Chemical …, 2024 - Elsevier
Chronic exposure to lead (Pb) induces neurodegenerative changes in animals and humans.
Drugs with strong antioxidant properties are effective against Pb-mediated neurotoxicity. In a …

Flavonoids as Potential Therapeutics Against Neurodegenerative Disorders: Unlocking the Prospects

M Faysal, Z Dehbia, M Zehravi, SH Sweilam… - Neurochemical …, 2024 - Springer
Neurodegeneration, the decline of nerve cells in the brain, is a common feature of
neurodegenerative disorders (NDDs). Oxidative stress, a key factor in NDDs such as …

The Involvement of Antioxidants in Cognitive Decline and Neurodegeneration: Mens Sana in Corpore Sano

C Nazzi, A Avenanti, S Battaglia - Antioxidants, 2024 - mdpi.com
With neurodegenerative disorders being on the rise, a great deal of research from multiple
fields is being conducted in order to further knowledge and propose novel therapeutic …