Physical activity, and specifically exercise, has been suggested as a potential treatment for
drug addiction. In this review, we discuss clinical and preclinical evidence for the efficacy of …

There is a high degree of overlap between brain regions involved in processing natural
rewards and drugs of abuse.“Non-drug” or “behavioral” addictions have become …

Accumulating research in rodents and humans indicates that exercise benefits brain function
and may prevent or delay onset of neurodegenerative conditions. In particular, exercise …

Numbers of overweight and obese individuals are increasing in the United States and
globally, and, correspondingly, the associated health care costs are rising dramatically …

Exercise provides a wealth of benefits to brain and body, and is regarded as a protective
factor against disease. Protective factors tend to cluster together–that is, people who engage …

Epidemiological studies reveal that individuals who engage in regular aerobic exercise are
less likely to use and abuse illicit drugs. Until recently, very few studies had examined the …

Exercise can enhance learning and memory and produce resistance against stress-related
psychiatric disorders such as depression and anxiety. In rats, these beneficial effects of …

Introduction: Exercise has been shown to be effective for preventing and treating substance
abuse in both clinical and preclinical studies. Less is known, however, regarding the …

The importance of studying sex as a biological variable in biomedical research is becoming
increasingly apparent. There is a particular need in preclinical studies of addiction to include …

Rationale Exposure to social defeat (SD) induces a depressive phenotype, increased
ethanol seeking and consumption, accompanied by activation of the neuroinflammatory …