Biological importance of structurally diversified chromenes

M Costa, TA Dias, A Brito, F Proença - European journal of medicinal …, 2016 - Elsevier
Compounds incorporating the chromene scaffold are largely present in natural products and
display a wide variety of biological activities. Their low toxicity combined to the broad …

Fungal endophytes as efficient sources of plant-derived bioactive compounds and their prospective applications in natural product drug discovery: Insights, avenues …

A Singh, DK Singh, RN Kharwar, JF White, SK Gond - Microorganisms, 2021 - mdpi.com
Fungal endophytes are well-established sources of biologically active natural compounds
with many producing pharmacologically valuable specific plant-derived products. This …

Galantamine improves cognition, hippocampal inflammation, and synaptic plasticity impairments induced by lipopolysaccharide in mice

Y Liu, Y Zhang, X Zheng, T Fang, X Yang, X Luo… - Journal of …, 2018 - Springer
Background Neuroinflammation plays an important role in the onset and progression of
neurodegenerative diseases such as Alzheimer's disease. Lipopolysaccharide (LPS …

[HTML][HTML] Lycium barbarum: a traditional Chinese herb and a promising anti-aging agent

Y Gao, Y Wei, Y Wang, F Gao, Z Chen - Aging and disease, 2017 - ncbi.nlm.nih.gov
Lycium barbarum has been used in China for more than 2,000 years as a traditional
medicinal herb and food supplement. Lycium barbarum contains abundant Lycium …

Target enzyme in Alzheimer's disease: Acetylcholinesterase inhibitors

M Saxena, R Dubey - Current topics in medicinal chemistry, 2019 - ingentaconnect.com
Alzheimer's Disease (AD), affecting a large population worldwide is characterized by the
loss of memory and learning ability in the old population. The enzyme Acetylcholinesterase …

Coumarins as fungal metabolites with potential medicinal properties

OM Tsivileva, OV Koftin, NV Evseeva - Antibiotics, 2022 - mdpi.com
Coumarins are a structurally varied set of 2 H-chromen-2-one compounds categorized also
as members of the benzopyrone group of secondary metabolites. Coumarin derivatives …

[HTML][HTML] Exercise and Urtica dioica extract ameliorate hippocampal insulin signaling, oxidative stress, neuroinflammation, and cognitive function in STZ-induced …

M Rahmati, M Keshvari, R Mirnasouri… - Biomedicine & …, 2021 - Elsevier
Introduction Diabetes mellitus is related to cognitive impairments and molecular
abnormalities of the hippocampus. A growing body of evidence suggests that Urtica dioica …

Coumarin: a privileged scaffold for the design and development of antineurodegenerative agents

E Jameel, T Umar, J Kumar… - Chemical biology & drug …, 2016 - Wiley Online Library
Drug development for neurodegenerative diseases (ND s) is foremost task for the medicinal
chemists in the 21st century. Coumarins are exemplary of an assorted and aptitudinally …

[HTML][HTML] Resistance training and Urtica dioica increase neurotrophin levels and improve cognitive function by increasing age in the hippocampus of rats

M Rahmati, M Keshvari, W Xie, G Yang, H Jin… - Biomedicine & …, 2022 - Elsevier
Introduction Inflammation and oxidative stress are two major factors in accelerating brain
aging. Consumption of some traditional herbs with antioxidant and anti-inflammatory …

Implication of coumarins towards central nervous system disorders

K Skalicka-Woźniak, IE Orhan, GA Cordell… - Pharmacological …, 2016 - Elsevier
Coumarins are widely distributed, plant-derived, 2 H-1-benzopyran-2-one derivatives which
have attracted intense interest in recent years as a result of their diverse and potent …