Fibrillarin is one of the most studied nucleolar proteins. Its main functions are methylation
and processing of pre-rRNA. Fibrillarin is a highly conserved protein; however, in the course …

The survival of motor neurons protein (SMN), the product of the neurodegenerative disease
spinal muscular atrophy (SMA) gene, functions as an assembly factor for snRNPs and likely …

The heterogeneous nuclear ribonucleoproteins (hnRNP) associate with pre-mRNA in the
nucleus and play an important role in RNA processing and splice site selection. In addition …

The methylation of arginine has been implicated in many cellular processes, such as
regulation of transcription, mRNA splicing, RNA metabolism and transport. The enzymes …

Methylation of arginine residues has been implicated in many cellular activities like mRNA
splicing, transcription regulation, signal transduction and protein–protein interactions …

Background Acute lymphoblastic leukemia (ALL) is the most frequently-occurring malignant
neoplasm in children, but the pathogenesis of the disease remains unclear. In a microarray …

Background: In this study, the possible relation of the expression pattern of arginine
methyltransferase 1 and colon cancer progression is investigated. Materials and Methods …

Protein arginine methyltransferases (PRMTs) regulate mRNA processing and maturation by
modulating the activity of RNA-binding proteins through methylation. The cDNA for human …

Fragile X syndrome results from the loss of a normal cellular protein, FMRP. FMRP is an
RNA binding protein, and it is likely that altering the way FMRP's messenger RNA (mRNA) …

Periconceptional folic acid supplementation can reduce the occurrence of neural tube
defects. A low folate status will result in reduced remethylation of homocysteine (Hcy) to …