Nucleolar methyltransferase fibrillarin: evolution of structure and functions
MY Shubina, YR Musinova, EV Sheval - Biochemistry (Moscow), 2016 - Springer
Fibrillarin is one of the most studied nucleolar proteins. Its main functions are methylation
and processing of pre-rRNA. Fibrillarin is a highly conserved protein; however, in the course …
and processing of pre-rRNA. Fibrillarin is a highly conserved protein; however, in the course …
SMN, the product of the spinal muscular atrophy gene, binds preferentially to dimethylarginine-containing protein targets
WJ Friesen, S Massenet, S Paushkin, A Wyce… - Molecular cell, 2001 - cell.com
The survival of motor neurons protein (SMN), the product of the neurodegenerative disease
spinal muscular atrophy (SMA) gene, functions as an assembly factor for snRNPs and likely …
spinal muscular atrophy (SMA) gene, functions as an assembly factor for snRNPs and likely …
The RGG domain in hnRNP A2 affects subcellular localization
RC Nichols, XW Wang, J Tang, BJN Hamilton… - Experimental cell …, 2000 - Elsevier
The heterogeneous nuclear ribonucleoproteins (hnRNP) associate with pre-mRNA in the
nucleus and play an important role in RNA processing and splice site selection. In addition …
nucleus and play an important role in RNA processing and splice site selection. In addition …
The PRMT1 gene expression pattern in colon cancer
K Mathioudaki, A Papadokostopoulou… - British journal of …, 2008 - nature.com
The methylation of arginine has been implicated in many cellular processes, such as
regulation of transcription, mRNA splicing, RNA metabolism and transport. The enzymes …
regulation of transcription, mRNA splicing, RNA metabolism and transport. The enzymes …
Clinical evaluation of PRMT1 gene expression in breast cancer
K Mathioudaki, A Scorilas, A Ardavanis, P Lymberi… - Tumor Biology, 2011 - Springer
Methylation of arginine residues has been implicated in many cellular activities like mRNA
splicing, transcription regulation, signal transduction and protein–protein interactions …
splicing, transcription regulation, signal transduction and protein–protein interactions …
Correlation of SRSF1 and PRMT1 expression with clinical status of pediatric acute lymphoblastic leukemia
Background Acute lymphoblastic leukemia (ALL) is the most frequently-occurring malignant
neoplasm in children, but the pathogenesis of the disease remains unclear. In a microarray …
neoplasm in children, but the pathogenesis of the disease remains unclear. In a microarray …
Colon cancer and protein arginine methyltransferase 1 gene expression
A Papadokostopoulou, K Mathioudaki… - Anticancer …, 2009 - ar.iiarjournals.org
Background: In this study, the possible relation of the expression pattern of arginine
methyltransferase 1 and colon cancer progression is investigated. Materials and Methods …
methyltransferase 1 and colon cancer progression is investigated. Materials and Methods …
Genomic organization, physical mapping, and expression analysis of the human protein arginine methyltransferase 1 gene
A Scorilas, MH Black, M Talieri… - … and biophysical research …, 2000 - Elsevier
Protein arginine methyltransferases (PRMTs) regulate mRNA processing and maturation by
modulating the activity of RNA-binding proteins through methylation. The cDNA for human …
modulating the activity of RNA-binding proteins through methylation. The cDNA for human …
Regulating a translational regulator: mechanisms cells use to control the activity of the fragile X mental retardation protein
RB Denman, N Dolzhanskaya, YJ Sung - Cellular and Molecular Life …, 2004 - Springer
Fragile X syndrome results from the loss of a normal cellular protein, FMRP. FMRP is an
RNA binding protein, and it is likely that altering the way FMRP's messenger RNA (mRNA) …
RNA binding protein, and it is likely that altering the way FMRP's messenger RNA (mRNA) …
Inhibition of transmethylation disturbs neurulation in chick embryos
LA Afman, HJ Blom, MJ Drittij, MR Brouns… - Developmental brain …, 2005 - Elsevier
Periconceptional folic acid supplementation can reduce the occurrence of neural tube
defects. A low folate status will result in reduced remethylation of homocysteine (Hcy) to …
defects. A low folate status will result in reduced remethylation of homocysteine (Hcy) to …