The past decades have witnessed great progress in cancer immunotherapy, which has
profoundly revolutionized oncology, whereas low patient response rates and potential …

Adjuvant is an essential component in subunit vaccines. Many agonists of pathogen
recognition receptors have been developed as potent adjuvants to optimize the …

Cancer immunotherapy and vaccine development have significantly improved the fight
against cancers. Despite these advancements, challenges remain, particularly in the clinical …

The development of nanovaccines that employ polymeric delivery carriers has garnered
substantial interest in therapeutic treatment of cancer and a variety of infectious diseases …

Conspectus The cyclic GMP-AMP synthase-stimulator interferon gene (cGAS-STING)
pathway is an emerging therapeutic target for the prophylaxis and therapy of a variety of …

Abstract STING (Stimulator of Interferon Genes) agonists have emerged as promising agents
in the field of cancer immunotherapy, owing to their excellent capacity to activate the innate …

Proteins are essential elements for almost all life activities. The emergence of
nanotechnology offers innovative strategies to create a diversity of nanoparticles (NPs) with …

The past few decades have witnessed the evolving paradigm for cancer therapy from
nonspecific cytotoxic agents to selective, mechanism‐based therapeutics, especially …

Innate immunity plays an important role not only during infection but also homeostatic role
during stress conditions. Activation of the immune system including innate immune response …

Targeting the stimulator of interferon genes (STING) pathway with cyclic dinucleotides
(CDNs), the natural STING agonists, is a promising immunotherapeutic strategy for cancer …