Transition-metal-catalyzed cross-coupling reactions have been well-established as
indispensable tools in modern organic synthesis. One of the major research goals in cross …

The incorporation of a synthetic, catalytically competent metallocofactor into a protein
scaffold to generate an artificial metalloenzyme (ArM) has been explored since the late …

Direct activation of gaseous hydrocarbons remains a major challenge for the chemistry
community. Because of the intrinsic inertness of these compounds, harsh reaction conditions …

C–H activation has emerged as a transformative tool in molecular synthesis, but until
recently oxidative C–H activations have largely involved the use of stoichiometric amounts of …

This review focuses on the postfunctionalization of porphyrins and related compounds
through catalytic and stoichiometric organometallic methodologies. The employment of …

In 2010 the emission of CO2 from anthropic activities amounted at ca. 30000 Mt, 43% of
which was from coal combustion, 36% from oil, and 20% from gas. 1 Growth of consumption …

Transition-metal-catalyzed nucleophilic addition of organometallic reagents to polar
unsaturated substrates is one of the most important and powerful bond-forming strategies …

The catalytic functionalization of unreactive C− H bonds has recently brought a revolution in
synthetic methodologies for the production of pharmaceuticals and natural products and for …

The cleavage of C–C bonds has been a great challenge owing to their thermodynamic and
kinetic stability. To date, the progress made in this area has mainly relied on the reaction of …

Research in the mid 1960s to early 1970s sparked an evolution in the approach of synthetic
chemists toward the assembly of molecules. Inspired by known Wacker-type processes in …