Cardiovascular and cerebrovascular diseases are the number one killer threatening
people's life and health, among which cardiovascular thrombotic events are the most …

Individual aged with various change in cell and cellular microenvironments and the skeletal
system undergoes physiological changes that affect the process of bone fracture healing …

Summary High interleukin (IL)-6 levels are associated with greater COVID-19 severity. IL-6
receptor blockade by tocilizumab (anti-IL6R; Actemra) is used globally for the treatment of …

While sub-clustering cell-populations has become popular in single cell-omics, negative
controls for this process are lacking. Popular feature-selection/clustering algorithms fail the …

Monocytes play a crucial role in immunity and tissue homeostasis. They constitute the first
line of defense during the inflammatory process, playing a role in the pathogenesis and …

Simple Summary Migration–proliferation dichotomy (MPD) is a characteristic that has been
observed in cancer cells growing in artificial culture media. The MPD principle states that …

Tocilizumab, an anti-interleukin-6 receptor inhibitor, is recommended in global treatment
guidelines for patients hospitalized with severe COVID-19. Using proteomic and …

Exploring the role of neuropeptides in the communication between monocyte subtypes
facilitates an investigation of the pathogenesis of Kawasaki disease (KD). We investigated …

Background & Aims: Hepatoblastoma (HB) is a rare form of pediatric liver cancer which is
currently treated with chemotherapy and surgery. The side effects of chemotherapy pose a …

Abstract High interleukin (IL)-6 levels are associated with more severe clinical
manifestations in patients hospitalized with COVID-19, but the complex role of IL-6 in …