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Summary Here, the International Myeloma Working Group (IMWG) updates its clinical
practice recommendations for the management of multiple myeloma-related renal …

The NCCN Guidelines for Multiple Myeloma provide recommendations for diagnosis,
workup, treatment, follow-up, and supportive care for patients with monoclonal gammopathy …

Abstract Continuous lenalidomide-dexamethasone (Rd)-based regimens are among the
standards of care in transplant-ineligible newly diagnosed multiple myeloma (NDMM) …

Importance Cast nephropathy is the main cause of acute kidney injury in multiple myeloma
and persistent reduction in kidney function strongly affects prognosis. Strategies to rapidly …

Major developments in the treatment of multiple myeloma (MM) over the past decade have
led to a continued improvement in survival. Significant progress has been made with deeper …

Background In multiple myeloma, severe acute kidney injury due to myeloma cast
nephropathy is caused by pathogenic free light chain immunoglobulin in serum. High cutoff …

Symptomatic multiple myeloma is commonly complicated by acute kidney injury through
various mechanisms. The most frequent is the precipitation of monoclonal free light chains …

Over the last two decades, the utilization of various novel therapies in the upfront or salvage
settings has continued to improve survival outcomes for patients with Multiple Myeloma …

Survival of myeloma patients has greatly improved with the use of autologous stem cell
transplantation and novel agents, such as proteasome inhibitors, immunomodulatory drugs …