Conspectus Transition metal hydride catalyzed functionalization of remote and proximal
olefins has many advantages over conventional cross-coupling reactions. It avoids the …

Compounds rich in sp3-hybridized carbons are desirable in drug discovery. Nickel-
catalyzed hydrocarbonation of alkenes is a potentially efficient method to synthesize these …

1, 2-Dicarbofunctionalization of alkenes has emerged as an efficient synthetic strategy for
preparing substituted molecules by coupling readily available alkenes with electrophiles …

Substantial advances in enantioconvergent C (sp3)–C (sp3) bond formations have been
made with nickel-catalyzed cross-coupling of racemic alkyl electrophiles with organometallic …

Enantioconvergent catalysis has expanded asymmetric synthesis to new methodologies
able to convert racemic compounds into a single enantiomer. This review covers recent …

Site-and enantio-selective alkyl–alkyl bond formation is privileged in the retrosynthetic
analysis due to the universality of sp3-hybridized carbon atoms in organic molecules …

To increase the reliability and success rate of drug discovery, efforts have been made to
increase the C (sp 3) fraction and avoid flat molecules. sp 3-Rich enantiopure amines are …

Although α-chiral C (sp 3)–S bonds are of enormous importance in organic synthesis and
related areas, the transition-metal-catalysed enantioselective C (sp 3)–S bond construction …

The pervasive occurrence of saturated stereogenic carbon centers in pharmaceuticals,
agrochemicals, functional organic materials, and natural products has stimulated great …

Abstract Enantioselective C (sp 3)–C (sp 3) coupling substantially impacts organic synthesis
but remains challenging. Cobalt has played an important role in the development of …