Available data on the absorption, metabolism and pharmacokinetics of coenzyme Q10
(CoQ10) are reviewed in this paper. CoQ10 has a fundamental role in cellular bioenergetics …

Mitochondrial disease confirmation and establishment of a specific molecular diagnosis
requires extensive clinical and laboratory evaluation. Dual genome origins of mitochondrial …

Female reproductive capacity declines dramatically in the fourth decade of life as a result of
an age‐related decrease in oocyte quality and quantity. The primary causes of reproductive …

Background Management of women with reduced ovarian reserve or poor ovarian response
(POR) to stimulation is one of the major challenges in reproductive medicine. The primary …

Background Trace elements and vitamins, named together micronutrients (MNs), are
essential for human metabolism. Recent research has shown the importance of MNs in …

Objectives Bioavailability of supplements with coenzyme Q10 (CoQ 10) in humans seems to
depend on the excipients of formulations and on physiological characteristics of the …

Heart failure (HF) with either preserved or reduced ejection fraction is associated with
increased morbidity and mortality. Evidence-based therapies are often limited by tolerability …

CoQ10 is an endogenous antioxidant produced in all cells that plays an essential role in
energy metabolism and antioxidant protection. CoQ10 distribution is not uniform among …

Coenzyme Q (CoQ) is a key component of the respiratory chain of all eukaryotic cells. Its
function is closely related to mitochondrial respiration, where it acts as an electron …

Antioxidants are endogenous and exogenous substances with the ability to inhibit oxidation
processes by interacting with reactive oxygen species (ROS). ROS, in turn, are small, highly …