Inspired by the biological processes of molecular recognition and transportation across
membranes, nanopore techniques have evolved in recent decades as ultrasensitive …

Proteins are responsible for the occurrence and treatment of many diseases, and therefore
protein sequencing will revolutionize proteomics and clinical diagnostics. Biological …

Proteins are the structural elements and machinery of cells responsible for a functioning
biological architecture and homeostasis. Advances in nanotechnology are catalyzing key …

Biological nanopores are nanoscale sensors employed for high-throughput, low-cost, and
long read-length DNA sequencing applications. The analysis and sequencing of proteins …

There are still unmet needs in finding new technologies for biomedical diagnostic and
industrial applications. A technology allowing the analysis of size and sequence of short …

Single-molecule measurements have greatly enhanced our understanding of living systems.
Biological systems offer nanopores, a sub-class of membrane proteins, the well-defined …

Membrane proteins mediate processes that are fundamental for the flourishing of biological
cells. Membrane-embedded transporters move ions and larger solutes across membranes; …

Single-molecule studies of protein folding hold keys to unveiling protein folding pathways
and elusive intermediate folding states attractive pharmaceutical targets. Although …

We report on the ability to control the dynamics of a single peptide capture and passage
across a voltage-biased, α-hemolysin nanopore (α-HL), under conditions that the …

Despite tremendous gains over the past decade, methods for characterizing proteins have
generally lagged behind those for nucleic acids, which are characterized by extremely high …