It is now firmly established that the contraction of muscle and many of the movements of
nonmuscle cells result from the interaction of two proteins, actin and myosin. These …

Steric blocking of actin-myosin interaction by tropomyosin has been a working hypothesis in
the study of the regulation of skeletal muscle contraction, yet the simple movement of actin …

We have used electron paramagnetic resonance (EPR) to investigate the orientation,
rotational motion, and actin-binding properties of rabbit psoas muscle cross-bridges in the …

Department of Biochemistry, University of Minnesota Medical School, Minneapolis,
Minnesota 55455 Received December 11, 1989; Revised Manuscript Received March 19 …

To study the orientation of spin-labeled myosin heads in the first few seconds after the
production of saturating ATP, we have used a laser flash to photolyze caged ATP during …

Tension responses due to small, rapid length changes (completed within 40 microseconds)
were obtained from skinned single frog muscle fiber segments (4–10 mm length) incubated …

Recent progress in the quantitative study of the mechanics, biochemistry, and molecular
structure of muscle has resulted in the formulation of detailed models for the molecular …