The mucus clearance system is the dominant mechanical host defense system of the human
lung. Mucus is cleared from the lung by cilia and airflow, including both two-phase gas-liquid …

Despite the advent of sophisticated and efficient new biologics to treat inflammation in
asthma, the disease persists. Even following treatment, many patients still experience the …

Mucus hydrogels at biointerfaces are crucial for protecting against foreign pathogens and for
the biological functions of the underlying cells. Since mucus can bind to and host both …

We seek to completely revise current models of airborne transmission of respiratory viruses
by providing never-before-seen atomic-level views of the SARS-CoV-2 virus within a …

Question Cystic fibrosis (CF) is characterised by the accumulation of viscous adherent
mucus in the lungs. While several hypotheses invoke a direct relationship with cystic fibrosis …

In the lung, the airway epithelium produces secreted and tethered mucin biopolymers to
form a mucus hydrogel layer and a surface-attached polymer brush layer. These layers work …

Mucus covers all wet epithelia and acts as a protective barrier. In the airways of the lungs,
the viscoelastic mucus meshwork entraps and clears inhaled materials and efficiently …

The surfaces of human internal organs are lined by a mucus layer that ensures symbiotic
relationships with commensal microbiome while protecting against potentially injurious …

Cystic fibrosis (CF) is a muco-obstructive lung disease where inflammatory responses due to
chronic infection result in the accumulation of neutrophil extracellular traps (NETs) in the …

Mucus obstruction is a key feature of many inflammatory airway diseases. Neutrophil
extracellular traps (NETs) are released upon neutrophil stimulation and consist of …