Sperm ion channels and transporters in male fertility and infertility

H Wang, LL McGoldrick, JJ Chung - Nature Reviews Urology, 2021 - nature.com
Mammalian sperm cells must respond to cues originating from along the female
reproductive tract and from the layers of the egg in order to complete their fertilization …

[HTML][HTML] miRNAs: The road from bench to bedside

G Iacomino - Genes, 2023 - mdpi.com
miRNAs are small noncoding RNAs that control gene expression at the posttranscriptional
level. It has been recognised that miRNA dysregulation reflects the state and function of cells …

Therapeutic use of mTOR inhibitors in renal diseases: advances, drawbacks, and challenges

SD Viana, F Reis, R Alves - Oxidative medicine and cellular …, 2018 - Wiley Online Library
The mammalian (or mechanistic) target of rapamycin (mTOR) pathway has a key role in the
regulation of a variety of biological processes pivotal for cellular life, aging, and death …

[HTML][HTML] Molecular pathophysiology of autosomal recessive polycystic kidney disease

A Cordido, M Vizoso-Gonzalez… - International Journal of …, 2021 - mdpi.com
Autosomal recessive polycystic kidney disease (ARPKD) is a rare disorder and one of the
most severe forms of polycystic kidney disease, leading to end-stage renal disease (ESRD) …

Autosomal dominant polycystic kidney disease: Disrupted pathways and potential therapeutic interventions

T Malekshahabi, N Khoshdel Rad… - Journal of cellular …, 2019 - Wiley Online Library
Autosomal dominant polycystic kidney disease (ADPKD) is a monogenic inherited renal
cystic disease that occurs in different races worldwide. It is characterized by the …

[HTML][HTML] Predicting autosomal dominant polycystic kidney disease progression: review of promising Serum and urine biomarkers

I Sorić Hosman, A Cvitković Roić, M Fištrek Prlić… - Frontiers in …, 2023 - frontiersin.org
Autosomal dominant polycystic kidney disease (ADPKD) is one of the leading causes of end-
stage renal disease. In spite of the recent tremendous progress in the understanding of …

[HTML][HTML] CystAnalyser: A new software tool for the automatic detection and quantification of cysts in Polycystic Kidney and Liver Disease, and other cystic disorders

A Cordido, E Cernadas… - PLoS computational …, 2020 - journals.plos.org
The Polycystic Kidney Disease (PKD) is characterized by progressive renal cyst
development and other extrarenal manifestation including Polycystic Liver Disease (PLD) …

[HTML][HTML] Ketogenic Interventions in Autosomal Dominant Polycystic Kidney Disease: A Comprehensive Review of Current Evidence

C Pezzuoli, G Biagini, R Magistroni - Nutrients, 2024 - mdpi.com
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a genetic disorder
characterized by the development and enlargement of multiple kidney cysts, leading to …

Prevalence of PKD1 gene mutation in cats in Turkey and pathogenesis of feline polycystic kidney disease

N Bilgen, M Bişkin Türkmen… - Journal of …, 2020 - journals.sagepub.com
Polycystic kidney disease (PKD) is one of the most common hereditary diseases in cats, with
high prevalence in Persian and Persian-related cats. PKD is caused mainly by an inherited …

[HTML][HTML] Metabolic changes in polycystic kidney disease as a potential target for systemic treatment

S Haumann, RU Müller, MC Liebau - International Journal of Molecular …, 2020 - mdpi.com
Autosomal recessive and autosomal dominant polycystic kidney disease (ARPKD, ADPKD)
are systemic disorders with pronounced hepatorenal phenotypes. While the main underlying …